Simultaneous Characterization of Implant Wear and Tribocorrosion Debris within its Corresponding Tissue Response Using Infrared Chemical Imaging

Liu, Songyun; Hall, D. W.; Valle, Craig J. Della; Jacobs, Joshua J.; Pourzal, Robin

doi:10.1016/j.biotri.2021.100163

Cited by 9 publications

(15 citation statements)

References 53 publications

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“…The SEM/EDS analysis of the pseudocapsule revealed large, mostly extracellular CoCrMo particles ranging in size from 1 µm to 7 µm (figure 6). Intracellularly, mostly chromium phosphate was observed as indicated by EDS mapping and confirmed by a strong characteristic phosphate ( ν (PO 4 3− ): 1200–900/cm) absorbance peak in their infrared spectra 10. FTIR univariate imaging of cardiac tissue demonstrated interstitial fibrosis and glycogen deposition (figure 7), which are hallmarks of cardiomyopathy pathology described by Mathlouthi and Koenig and Colagar et al 11 12.…”

Section: Resultsmentioning

confidence: 62%

Non-ischaemic cardiomyopathy associated with elevated serum cobalt and accelerated wear of a metal-on-metal hip resurfacing

et al. 2022

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A man in his late 30s developed non-ischaemic cardiomyopathy due to systemic cobalt toxicity associated with accelerated bearing surface wear from metal-on-metal hip resurfacing implanted in the previous 6 years. Following revision arthroplasty, the patient regained baseline cardiac function. Cobalt-induced cardiomyopathy is a grave condition that deserves early consideration due to potentially irreversible morbidity. We present this case to increase awareness, facilitate early detection and emphasise the need for research into the diagnosis and management of at-risk patients.

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Section: Resultsmentioning

confidence: 62%

Non-ischaemic cardiomyopathy associated with elevated serum cobalt and accelerated wear of a metal-on-metal hip resurfacing

et al. 2022

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“…The nature of particles was studied using reflectance FTIR microscopy (Figure 1). 29 Inorganic phosphates are composed of a tetrahedral PO 4 3− anions, which in the mid‐infrared region exhibit characteristic strong and broad peak in region 1180–1000 cm −1 corresponding to asymmetric stretching vibrations, and peak in region 600–500 cm −1 corresponding to bending vibrations of phosphate anion 30–32 . Additionally, IR spectra of all samples were characterized by peaks related to the collagen network of joint capsule tissue 5 .…”

Section: Resultsmentioning

confidence: 98%

“…29 Inorganic phosphates are composed of a tetrahedral PO 4 3À anions, which in the mid-infrared region exhibit characteristic strong and broad peak in region 1180-1000 cm À1 corresponding to asymmetric stretching vibrations, and peak in region 600-500 cm À1 corresponding to bending vibrations of phosphate anion. [30][31][32] Additionally, IR spectra of all samples were characterized by peaks related to the collagen network of joint capsule tissue. 5 Spectra exhibit characteristic peaks for amides in regions 1700-1500 cm À1 and 1300-1800 cm À1 , and for lipids in region 3000-2800 cm À1 .…”

Section: Speciation In Pseudosynovial Membrane In Direct Contact With...mentioning

confidence: 99%

Detailed insight into chromium species released from failed CoCrMo implants: Ex vivo periprosthetic tissues study

et al. 2022

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This unique study provides information on Cr species and their distribution in periprosthetic tissues of patients with metal-on-polyethylene joint implants. Co-Cr-Mo alloy has been widely used in joint replacement and represents a source of metal derived species. In the case of chromium, previous studies on periprosthetic tissues revealed mainly Cr(III) distribution, whereas the potential release of carcinogenic Cr(VI) species has been still a subject of debate. Here, an analytical approach utilizing speciation and fractionation was developed to analyze periprosthetic tissue samples collected from wide range of patients with failed total hip or knee replacements. The results reveal that Cr(III) is mainly released in the form of insoluble CrPO 4 and Cr 2 O 3 particles. The highest Cr contents were found in periprosthetic tissues of patients suffering from aseptic loosening and having more Cr-based implants in the body. Cr species penetrated tissue layers, but their levels decreased with the distance from an implant. The detailed speciation/fractionation study carried out using the set of consecutive periprosthetic tissues of a patient with extensive metallosis showed the presence of trace amounts of free Cr(III), nanoparticles, and metal-protein complexes, but the majority of Cr still occurred in CrPO 4 form. Carcinogenic Cr(VI) species were not detected. Up to date, there is no published human tissue study focused on the detailed speciation of both soluble and insoluble Cr-based species in the context of failing total hip and knee replacements.

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“…Tribological approaches generally consisted of wear studies through laboratory and clinical means, while lubrication was mainly investigated through computational methods [657]. Wear of the contact surfaces was important, as well as the characterization of wear debris with novel imaging techniques [658]. A new wear measurement technique was developed through a chemical means [659], therefore capable of differentiating the top and the bottom wear of the tibial insert in the knee implant.…”

Section: Natural Synovial Joints and Artificial Joint Replacementsmentioning

confidence: 99%

A review of advances in tribology in 2020–2021

Meng

et al. 2022

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Around 1,000 peer-reviewed papers were selected from 3,450 articles published during 2020–2021, and reviewed as the representative advances in tribology research worldwide. The survey highlights the development in lubrication, wear and surface engineering, biotribology, high temperature tribology, and computational tribology, providing a show window of the achievements of recent fundamental and application researches in the field of tribology.

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Simultaneous Characterization of Implant Wear and Tribocorrosion Debris within its Corresponding Tissue Response Using Infrared Chemical Imaging

Cited by 9 publications

References 53 publications

Non-ischaemic cardiomyopathy associated with elevated serum cobalt and accelerated wear of a metal-on-metal hip resurfacing

Non-ischaemic cardiomyopathy associated with elevated serum cobalt and accelerated wear of a metal-on-metal hip resurfacing

Detailed insight into chromium species released from failed CoCrMo implants: Ex vivo periprosthetic tissues study

A review of advances in tribology in 2020–2021

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