Simultaneous Densitometric Determination of 6‐Gingerol and 6‐Shogaol in some Commercial Gingers (<i>Zingiber Officinale</i>Roscoe)

Melianita, Fenny; Sumarlik, Endang; Kartinasari, Wiwin Farina; Indrayanto, Gunawan

doi:10.1080/10826070701589016

Cited by 7 publications

(4 citation statements)

References 11 publications

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“…Recovery studies were performed by the method of standard addition and this method showed the excellent reliability and reproducibility with recovery values from 99.79 to 99.84%. Melianita et al (2007) developed a rapid as well as a simple densitometric method for determination of [6]-gingerol and [6]-shogaol, which can be used for routine analysis of ginger samples in herbal drugs industry quality control laboratories.…”

Section: Gc-ms Analysis Of Volatile Compoundsmentioning

confidence: 99%

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

Kubra

Rao

2012

Critical Reviews in Food Science and Nutrition

165

118

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Ginger rhizome (Zingiber officinale Roscoe) is widely cultivated as a spice for its aromatic and pungent components. The essential oil and oleoresins from ginger are valuable products responsible for the characteristic flavor and pungency. Both are used in several food products such as soft beverages and also in many types of pharmaceutical formulations. More than 100 compounds have been reported from ginger, some of which are isolated and characterized, others are tentatively identified by GC-MS and / or LC-MS. [6]-Gingerol, the major gingerol in ginger rhizomes, has been found to possess many interesting pharmacological and physiological activities, such as anti-inflammatory, analgesic, and cardiotonic effects. Ginger is considered as "generally recognized as safe" (GRAS) by Food and Drug Administration (FDA), USA. Due to all these properties, ginger has gained considerable attention in developed countries in recent years, especially for its use in the treatment of inflammatory conditions. The present review is a persuasive presentation of the current information on processing, chemistry, biological activities, and medicinal uses of ginger. Further studies are required for the validation of the beneficial uses. Formulation for novel products and new usages may emerge in the years to come, based on the revealed results of various studies.

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Section: Gc-ms Analysis Of Volatile Compoundsmentioning

confidence: 99%

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

Kubra

Rao

2012

Critical Reviews in Food Science and Nutrition

165

118

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“…Many quantitative methods have been applied to the analysis of gingerols (Bhattarai, Tran, and Duke 2001;Lee et al 2007;Melianita et al 2007;Rai et al 2006;Schwertner and Rios 2007;Wang et al 2002). Among these methods, HPLC has been considered to be a powerful tool for determination of gingerols in ginger.…”

Section: Introductionmentioning

confidence: 99%

Rapid and Accurate Analytical Method for the Determination of Gingerols in Three Medicinal Gingers (Zingiber officinaleRoscoe) by High Performance Liquid Chromatography

Zhu

et al. 2008

Analytical Letters

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A rapid, simple, sensitive, and accurate high performance liquid chromatographic (HPLC) method has been developed and validated for the simultaneous determination of 6-gingerol, 8-gingerol, and 10-gingerol in three medicinal gingers. The chromatographic separation of three gingerols was achieved within 4 min on a sub-2 mm particles column. Gradient elution was performed using acetonitrile-water as the mobile phase at a flow rate of 1.0 mL=min. The injection volume was 2 mL, and the detection wavelength was set at 280 nm. Validation studies revealed that the method was reliable and reproducible for the simultaneous quantitation of the three gingerols in three medicinal gingers.

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“…In continuation of our work on standardization of Ayurvedic formulations [23], we planned to evaluate 6-gingerol in this formulation and in market and Suprabha ginger, a variety of ginger is cultivated in Patangi of Koraput district, Orissa. Many TLC and HPTLC methods have been reported for quantitative analysis of 6-gingerol in ginger [24][25][26]. Moreover, the HPTLC method described in this paper is inexpensive, rapid, and more sensitive than previously reported methods.…”

Section: Introductionmentioning

confidence: 91%

Efficient and sensitive method for quantitative analysis of 6-gingerol in marketed Ayurvedic formulation

Rout

Mishra

2009

Journal of Planar Chromatography – Modern TLC

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An efficient, sensitive, and precise high-performance thin-layer chromatographic (HPTLC) method has been established for analysis of 6-gingerol in marketed Ayurvedic formulations and in the rhizomes of different varieties of Zingiber officinale. HPTLC separation was performed on aluminum foil-backed HPTLC plates coated with 0.2-mm layers of silica gel 60 F 254 , with n-hexane-acetone, 7.2:2.8 (v/v) as mobile phase. Plates were developed to a distance of 78 mm at 20 ± 4°C in a chamber previously saturated for 4 min. Under these condition the retention factor (R F ) of 6-gingerol was 0.23 and the compound was quantified at 286 nm, its wavelength of maximum absorbance. The limits of detection and quantification were 40 and 150 ng per band, respectively. Response to 6-gingerol was a linear function of amount over the range 150 to 900 ng per band; the correlation coefficient was 0.9997, indicating a good relationship between peak area and amount. Recovery from 98.46 to 101.11% showed the accuracy of the method was excellent. The method is very accurate, simple, and cost effective, and enables sensitive quantitative analysis of 6-gingerol.

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Simultaneous Densitometric Determination of 6‐Gingerol and 6‐Shogaol in some Commercial Gingers (Zingiber OfficinaleRoscoe)

Cited by 7 publications

References 11 publications

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

Rapid and Accurate Analytical Method for the Determination of Gingerols in Three Medicinal Gingers (Zingiber officinaleRoscoe) by High Performance Liquid Chromatography

Efficient and sensitive method for quantitative analysis of 6-gingerol in marketed Ayurvedic formulation

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