Simultaneous determination of cobalt and nickel in vitamin B12 samples using high-resolution continuum source atomic absorption spectrometry

Adolfo, Franciéle Rovasi; Nascimento, Paulo Cı́cero do; Bohrer, Denise; Carvalho, Leandro Machado de; Viana, Carine; Guarda, Ananda; Colim, Alexsandro Nunes; Mattiazzi, Patrícia

doi:10.1016/j.talanta.2015.09.073

Cited by 43 publications

(11 citation statements)

References 7 publications

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“…Vitamin B 12 (α-(5, 6-dimethylbenzimidazolyl) cobamidcyanide), also named cobalamin since it contains cobalt in the core of its molecular structure, is one of eight known B vitamins [1]. These vitamins are water-soluble and are essential for normal human growth, development, and metabolism [2].…”

Section: Introductionmentioning

confidence: 99%

Vitamin B12 and Semen Quality

Banihani

2017

Biomolecules

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Various studies have revealed the effects of vitamin B12, also named cobalamin, on semen quality and sperm physiology; however, these studies collectively are still unsummarized. Here, we systematically discuss and summarize the currently understood role of vitamin B12 on semen quality and sperm physiology. We searched the Web of Science, PubMed, and Scopus databases for only English language articles or abstracts from September 1961 to March 2017 (inclusive) using the key words “vitamin B12” and “cobalamin” versus “sperm”. Certain relevant references were included to support the empirical as well as the mechanistic discussions. In conclusion, the mainstream published work demonstrates the positive effects of vitamin B12 on semen quality: first, by increasing sperm count, and by enhancing sperm motility and reducing sperm DNA damage, though there are a few in vivo system studies that have deliberated some adverse effects. The beneficial effects of vitamin B12 on semen quality may be due to increased functionality of reproductive organs, decreased homocysteine toxicity, reduced amounts of generated nitric oxide, decreased levels of oxidative damage to sperm, reduced amount of energy produced by spermatozoa, decreased inflammation-induced semen impairment, and control of nuclear factor-κB activation. However, additional research, mainly clinical, is still needed to confirm these positive effects.

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Section: Introductionmentioning

confidence: 99%

Vitamin B12 and Semen Quality

Banihani

2017

Biomolecules

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“…Cobalt is found in the human body at small levels, with 85% in the form of vitamin B12 primarily derived from drinking or eating Co containing foods [73]. Cobalt, as one of the essential minerals for human health, possesses a key function in several biochemical activities such as biosynthesis of nucleic acids and amino acids, as well as erythrocytes production [74]. Nowadays, lots of cobalt (Co)-containing dietary supplements are sold on the market, and many producers have suggested a daily dose up to 1 mg to aid in metabolizing fat and carbohydrates, protein and red blood cell formation [75].…”

Section: Cobaltmentioning

confidence: 99%

Dietary Micronutrients from Zygote to Senility: Updated Review of Minerals’ Role and Orchestration in Human Nutrition throughout Life Cycle with Sex Differences

et al. 2021

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Micronutrients such as selenium, fluoride, zinc, iron, and manganese are minerals that are crucial for many body homeostatic processes supplied at low levels. The importance of these micronutrients starts early in the human life cycle and continues across its different stages. Several studies have emphasized the critical role of a well-balanced micronutrient intake. However, the majority of studies looked into or examined such issues in relation to a specific element or life stage, with the majority merely reporting the effect of either excess or deficiency. Herein, in this review, we will look in depth at the orchestration of the main element requirements across the human life cycle beginning from fertility and pregnancy, passing through infancy, childhood, adolescence, and reaching adulthood and senility, with insight on the interactions among them and underlying action mechanisms. Emphasis is given towards approaches to the role of the different minerals in the life cycle, associated symptoms for under- or overdoses, and typical management for each element, with future perspectives. The effect of sex is also discussed for each micronutrient for each life stage as literature suffice to highlight the different daily requirements and or effects.

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“…Cobalt is an essential element for plants, animals, and human beings, needed in a small amount in the diet to conduct its daily requirement. As an integral part of the only metal-containing vitamin, B 12 , cobalt plays an important role in some biochemical processes, e.g., synthesis of nucleic acids and amino acids (Adolfo et al 2016;Stoica et al 2004). Vitamin B 12 or cobalamin is an essential vitamin for the human organism, stored in the liver.…”

Section: Introductionmentioning

confidence: 99%

Study of bioaccessibility of cobalt species in berries and seeds by mass spectrometry techniques

Wojcieszek

Ruzik

2020

J Anal Sci Technol

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In recent years, açai berries (Euterpe Oleracea M.), goji berries (Lycium barbarum L.), bilberries (Vaccinium myrtillus L.), and chia seeds (Salvia hispanica L.) have increased interest worldwide due to their nutritional value and health benefits. In the present study, SEC-ICP-MS and μ-HPLC-ESI-MS/MS were used for the investigation of cobalt speciation and evaluation of its bioaccessibility in these products. Total cobalt content was determined, and açai berries (0.348 ± 0.042 μg g −1) and chia seeds (0.352 ± 0.036 μg g −1) were found as the best sources of this element. Different elution profiles of the extracts of examined berries and seeds obtained with the use of ammonium acetate, Tris-HCl, and SDS suggested that cobalt is bound by different bioligands in each biomatrix. The bioaccessibility of cobalt species was evaluated by SEC-ICP-MS. On the chromatograms of extracts obtained after simulation of gastrointestinal digestion, peaks corresponding to low molecular mass (17.00-1.35 kDa) cobalt complexes were observed. In the case of goji berries, their intensities were significantly higher on chromatograms of gastrointestinal than gastric extract. In enzymatic extracts, different forms of vitamin B 12 were identified by μ-HPLC-ESI-MS, including its natural forms-methylcobalamin (Me-Cbl) and adenosylcobalamin (Ado-Cbl).

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Simultaneous determination of cobalt and nickel in vitamin B12 samples using high-resolution continuum source atomic absorption spectrometry

Cited by 43 publications

References 7 publications

Vitamin B12 and Semen Quality

Vitamin B12 and Semen Quality

Dietary Micronutrients from Zygote to Senility: Updated Review of Minerals’ Role and Orchestration in Human Nutrition throughout Life Cycle with Sex Differences

Study of bioaccessibility of cobalt species in berries and seeds by mass spectrometry techniques

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