Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography

“…The inter-day (n = 3) and intra-day (n = 8) repeatability were evaluated for the retention times, peak areas, and peak heights of sodium benzoate and potassium sorbate by eight successive injections of each analytical standard with concentration of 120.16 and 243.84 mg L −1 , respectively (Table II) [26].…”

Section: Resultsmentioning

confidence: 99%

Development of reverse-phase high-performance liquid chromatography method for simultaneous determination of sodium benzoate and potassium sorbate in beverages

Petanovska‐Ilievska

Velkoska-Markovska

Jankulovska

2017

Acta Chromatographica

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Summary.Reverse-phase high-performance liquid chromatography (RP-HPLC) method for simultaneous determination of sodium benzoate and potassium sorbate in beverages was developed using high speed column. The simple and rapid reverse-phase method for quantitative determination of both preservatives was established on LiChroCART ® Purospher STAR RP-18e (30 mm × 4 mm; 3 μm) column, mobile phase consisted of acetonitrile-phosphate buffer (pH = 3.5) in volume ratio of 8:92 (v/v), flow rate of 1 mL min −1 , ultraviolet (UV) detection at 195 nm for sodium benzoate and 260 nm for potassium sorbate, and constant column temperature at 25 °C. Linearity, precision, accuracy, limit of quantification (LOQ), and limit of detection (LOD) were tested for method validation. Linearity range for sodium benzoate was 6.04-200.27 mg L −1 (R 2 = 0.999) while, for potassium benzoate (R 2 = 0.999), 12.19-406.36 mg L −1 . The RSD values ≤1.03% demonstrate excellent intra-day precision. LOD for sodium benzoate and potassium sorbate was 0.004 and 0.003 mg L −1 , while LOQ was 0.012 and 0.009 mg L −1 , respectively. This method was applied for quantitative determination of investigated preservatives in beverages which were taken from Macedonian markets.

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“…These tow parabens were selected because they are the most frequently used in cosmetic products (e.g., creams, skin lotions or gels). Moreover, MP and PP are often used together due to their synergistic effects [2].…”

Section: Introductionmentioning

confidence: 99%

“…It was found that on the using water as solvent for methyl paraben and acetone for o-CA in the case of methyl and ethanol propyl in the presence of KOH and dilution with the same solvent were gave maximum color intensity. Table(2) show the effect of acetone amount on the signal absorption, different percentages from 0.0% -100% were used in this study as shown in table (2), the maximum absorbance selected as optiumum concentration of acetone was 60%. …”

Section: Effect Of Solvent Typementioning

confidence: 99%

Spectrophotometric method for the microdetermination of methyl and propyl paraben in some detergents through charge transfer complex

Yahyaa¹

2017

Irq. Nat. J. Chem.

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AbstracSimple Spectral method was developed to estimate the methyl and propyl paraben through charge-transfer (CT) complexes. The method involves the interaction of parabens compounds with o-chloranil as π-acceptor. Under the optimized conditions, the complexes were found to be absorbed at 415 and 385 nm with in the linearity range of 5-40 and 5-55 μg ml -1 respectively. The molar absorptivity values were in the range 3803.75 and 2342.6 L.mol -1 .cm -1 respectively. And the lower limit of detection were in the rang 0.073 and 0.086 µg/ml -1 for methyl and propyl respectively. The stoichiometry of the paraben compounds o-chloranil complexes was found to be 1:1 method. The procedure was characterized by its simplicity with accuracy and precision. The proposed method was applied successful in some detergents (shampoo and lotion) containing paraben compounds.

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Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography

Cited by 248 publications

References 12 publications

Simultaneous Determination of NSAID and Antimicrobial Preservatives Using Validated RP-HPLC Method: An Application in Pharmaceutical and Clinical Laboratories

Simultaneous Determination of NSAID and Antimicrobial Preservatives Using Validated RP-HPLC Method: An Application in Pharmaceutical and Clinical Laboratories

Development of reverse-phase high-performance liquid chromatography method for simultaneous determination of sodium benzoate and potassium sorbate in beverages

Spectrophotometric method for the microdetermination of methyl and propyl paraben in some detergents through charge transfer complex

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