Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid using Au decorated carbon nanofibers modified screen printed electrode

Sakthivel, P.; Ramachandran, K.; Maheshvaran, K.; Senthil, T. S.; Manivel, P.

doi:10.1007/s42823-024-00759-5

Carbon Lett.

2024

DOI: 10.1007/s42823-024-00759-5

|View full text |Cite

Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid using Au decorated carbon nanofibers modified screen printed electrode

P. Sakthivel,

K. Ramachandran,

K. Maheshvaran

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

A Portable Microelectrochemical Sensor Based on Potentiostatic Polarization-Treated and Laser-Induced Graphene for the Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid

Yuan,

Wu,

et al. 2024

Langmuir

View full text Add to dashboard Cite

Maintaining normal biomolecular levels in the human body plays a crucial role in controlling various diseases. In this work, we designed a portable microelectrochemical sensor based on laserinduced graphene (LIG) for the simultaneous determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). A simple electrode surface modification strategy, potentiostatic polarization in an alkali solution, was applied to functionalize the LIG surface with the aim of enhancing the LIG electrocatalytic activity, conductivity, and wettability. After electrochemical pretreatment, the modified electrode displayed significantly enhanced electrocatalytic activity toward AA, DA, and UA, with well-separated characteristic oxidation peaks for each analyte, thus achieving their simultaneous detection without further modification by nanomaterials. Differential pulse voltammetry (DPV) was applied for determining these three analytes. Under optimal conditions, calibration curves were obtained in the ranges 10−5000 μM, 0.1−6000 μM, and 10−8000 nM for AA, DA, and UA, with the detection limits (S/N = 3) of 1.43 μM, 6.83 nM, and 1.07 nM, respectively. The microelectrochemical sensor achieved reliable and satisfactory results in detecting AA, DA, and UA in actual urine samples, demonstrating significant application prospects in human health monitoring and clinical diagnosis.

show abstract

A Portable Microelectrochemical Sensor Based on Potentiostatic Polarization-Treated and Laser-Induced Graphene for the Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid

Yuan,

Wu,

et al. 2024

Langmuir

View full text Add to dashboard Cite

show abstract

Interdigitated Gear-Shaped Screen-Printed Electrode Using G-PANI Ink for Sensitive Electrochemical Detection of Dopamine

Sarkar,

Tabassum,

Jalal

et al. 2024

JSAN

View full text Add to dashboard Cite

In this research, a novel interdigitated gear-shaped, graphene-based electrochemical biosensor was developed for the detection of dopamine (DA). The sensor’s innovative design improves the active surface area by 94.52% and 57% compared to commercially available Metrohm DropSens 110 screen-printed sensors and printed circular sensors, respectively. The screen-printed electrode was fabricated using laser processing and modified with graphene polyaniline conductive ink (G-PANI) to enhance its electrochemical properties. Fourier Transform Infrared (FTIR) Spectroscopy and X-ray diffraction (XRD) were employed to characterize the physiochemical properties of the sensor. Dopamine, a neurotransmitter crucial for several body functions, was detected within a linear range of 0.1–100 µM, with a Limit of Detection (LOD) of 0.043 µM (coefficient of determination, R2 = 0.98) in phosphate-buffer saline (PBS) with ferri/ferrocyanide as the redox probe. The performance of the sensor was evaluated using cyclic voltammetry (CV) and Chronoamperometry, demonstrating high sensitivity and selectivity. The interdigitated gear-shaped design exhibited excellent repeatability, with a relative standard deviation (RSD) of 1.2% (n = 4) and reproducibility, with an RSD of 2.3% (n = 4). In addition to detecting dopamine in human serum, the sensor effectively distinguished dopamine in a ternary mixture containing uric acid (UA) and ascorbic acid (AA). Overall, this novel sensor design offers a reliable, disposable, and cost-effective solution for dopamine detection, with potential applications in medical diagnostics and neurological research.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid using Au decorated carbon nanofibers modified screen printed electrode

Cited by 2 publications

References 61 publications

A Portable Microelectrochemical Sensor Based on Potentiostatic Polarization-Treated and Laser-Induced Graphene for the Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid

A Portable Microelectrochemical Sensor Based on Potentiostatic Polarization-Treated and Laser-Induced Graphene for the Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid

Interdigitated Gear-Shaped Screen-Printed Electrode Using G-PANI Ink for Sensitive Electrochemical Detection of Dopamine

Contact Info

Product

Resources

About