Simultaneous electrochemical determination of ascorbic acid, dopamine and uric acid with helical carbon nanotubes

Zhang, Bingyan; Huang, Dekang; Xu, Xiaobao; Alemu, Getachew; Zhang, Hongjie; Zhan, Fenghuang; Shen, Yan; Wang, Mingkui

doi:10.1016/j.electacta.2012.12.026

Cited by 99 publications

(34 citation statements)

References 39 publications

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“…The detection limit (S/N = 3) was calculated to be 0.22 μM, value which is comparable with the lowest LOD reported in literature, being 50 times lower than other methods employing electrodes modified with CDs, Table 4 [1,6–21]. …”

Section: Resultssupporting

confidence: 81%

New β-Cyclodextrin Entrapped in Polyethyleneimine Film-Modified Electrodes for Pharmaceutical Compounds Determination

Fritea

Tertiş

Cristea

et al. 2013

Sensors

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Abstract:The electrochemical behavior of ascorbic acid and uric acid on glassy carbon bare electrodes and ones modified with β-cyclodextrin entrapped in polyethyleneimine film has been investigated using square wave voltammetry. The electrode modification was achieved in order to separate the voltammetric peaks of ascorbic acid and uric acid when present in the same solution. On the modified electrodes the potential of the oxidation peak of the ascorbic acid was shifted to more negative values by over 0.3 V, while in the case of uric acid, the negative potential shift was about 0.15 V compared to the bare glassy carbon electrode. When the two compounds were found together in the solution, on the bare electrode only a single broad signal was observed, while on the modified electrode the peak potentials of these two compounds were separated by 0.4 V. When the uric acid concentration remained constant, the peak intensity of the ascorbic acid is increased linearly with the concentration (r 2 = 0.996) and when the ascorbic acid concentration remains constant, the peak intensity of the uric acid increased linearly with the concentration (r 2 = 0.992). FTIR measurements supported the formation of inclusion complexes. In order to characterize the modification of the electrodes microscopic studies were performed. The modified electrodes were successfully employed for the determination of ascorbic acid in pharmaceutical formulations with a detection limit of 0.22 µM.

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Section: Resultssupporting

confidence: 81%

New β-Cyclodextrin Entrapped in Polyethyleneimine Film-Modified Electrodes for Pharmaceutical Compounds Determination

Fritea

Tertiş

Cristea

et al. 2013

Sensors

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“…[44,45] A HCNT has a 3D-helical structure with high specific surface area and good electronic properties due to the rupture of the basal plane on the end caps of CNTs that leads to a larger density of edge-plane like defects on the nanotube surface. [46] Poly(allylamine hydrochloride) (PAH) and poly(diallyl dimethylammonium chloride) (PDDA) were used to functionalize the nanotube surface and disperse the HCNTs.…”

Section: 0 Neurotransmitters/neurochemicalsmentioning

confidence: 99%

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

Yang

Denno

Pyakurel

et al. 2015

Analytica Chimica Acta

494

263

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Carbon nanomaterials are advantageous for electrochemical sensors because they increase the electroactive surface area, enhance electron transfer, and promote adsorption of molecules. Carbon nanotubes (CNTs) have been incorporated into electrochemical sensors for biomolecules and strategies have included the traditional dip coating and drop casting methods, direct growth of CNTs on electrodes and the use of CNT fibers and yarns made exclusively of CNTs. Recent research has also focused on utilizing many new types of carbon nanomaterials beyond CNTs. Forms of graphene are now increasingly popular for sensors including reduced graphene oxide, carbon nanohorns, graphene nanofoams, graphene nanorods, and graphene nanoflowers. In this review, we compare different carbon nanomaterial strategies for creating electrochemical sensors for biomolecules. Analytes covered include neurotransmitters and neurochemicals, such as dopamine, ascorbic acid, and serotonin; hydrogen peroxide; proteins, such as biomarkers; and DNA. The review also addresses enzyme-based electrodes that are used to detect non-electroactive species such as glucose, alcohols, and proteins. Finally, we analyze some of the future directions for the field, pointing out gaps in fundamental understanding of electron transfer to carbon nanomaterials and the need for more practical implementation of sensors.

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“…CNTs play a key role in sensing performance due to their ability to promote fast electron transfer reactions. On the other hand, the electrocatalytic properties of CNTs are strongly dependent on the fabrication mode and dispersing agent used to immobilize them on the electrodes surface [13][14][15][16][17][18][19][20]. Several studies have been made using CP/CNT composite electrodes to measure DA [6,21,22] but very few have attempted to measure AA, DA, and UA simultaneously [23].…”

Section: Introductionmentioning

confidence: 99%

Chemometric Strategies to Develop a Nanocomposite Electrode for Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid

2013

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A simple and sensitive method for simultaneously measuring dopamine (DA), ascorbic acid (AA), and uric acid (UA) using a poly(1-aminoanthracene) and carbon nanotubes nanocomposite electrode is presented. The experimental parameters for composite film synthesis as well as the variables related to simultaneous determination of DA, AA, and UA were optimized at the same time using fractional factorial and Doehlert designs. The use of carbon nanotubes and poly(1-aminoanthracene) in association with a cathodic pretreatment led to three well-defined oxidation peaks at potentials around À0.039, 0.180 and 0.351 V (vs. Ag/AgCl) for AA, DA, and UA, respectively. Using differential pulse voltammetry, calibration curves for AA, DA, and UA were obtained over the range of 0.16-3.12 10 À3 mol L , respectively. The proposed method was successfully applied to determine DA, AA, and UA in biological samples with good results.

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Simultaneous electrochemical determination of ascorbic acid, dopamine and uric acid with helical carbon nanotubes

Cited by 99 publications

References 39 publications

New β-Cyclodextrin Entrapped in Polyethyleneimine Film-Modified Electrodes for Pharmaceutical Compounds Determination

New β-Cyclodextrin Entrapped in Polyethyleneimine Film-Modified Electrodes for Pharmaceutical Compounds Determination

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

Chemometric Strategies to Develop a Nanocomposite Electrode for Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid

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