Coastal areas often experience high population density and intense human activity owing to the considerable value of the ocean. Therefore, devices for monitoring marine disasters are crucial for ensuring the safety of human life. Herein, we develop hemispherical spring origami (SO) triboelectric nanogenerators (TENGs) (HSO-TENGs) for self-powered ocean wave monitoring. Optimization is performed using two approaches. First, swing machine experiments are conducted to investigate the monitoring performance of the HSO-TENGs regarding wave height and period with satisfactory accuracy. To increase power generation and monitoring accuracy, the internal inertia and centroid of gravity of the HSO-TENGs are optimized with respect to the structural parameters (i.e., magnet weight, hammer height, and external swing arm length). Second, numerical simulations are performed using the smoothed-particle hydrodynamics (SPH) method to determine the most suitable fixed condition for the HSO-TENGs for sensing wave changes. Subsequently, wave tank experiments are conducted on the HSO-TENGs to determine their ability to sense wave height, period, frequency, and direction. Tests related to supplying other sensors are also conducted. Eventually, the ability of the HSO-TENGs to monitor wave direction and spreading parameters is investigated in a numerical SPH circular wave tank. The results prove that the optimized HSO-TENGs can achieve powering and sensing through the same device.