Simultaneous indicators of inadequate breast milk intake in the early neonatal period

Abstract

line-associated bloodstream infections among extremely preterm infants with a gestational age of <26 weeks. 2 In our study, 82 extremely preterm infants were included: 40 in 2011-2013 (the 0.5% CHG-70% alcohol cohort) and 42 in 2013-2015 (the 0.2% CHG acetate cohort). The incidence of chemical burns was lower in the 0.2% CHG-acetate cohort (2/41 [4.9%]; 95% CI, 0.8%-15.2%) compared with the 0.5% CHG-70% alcohol cohort (9/41 [22.0%]; 95% CI, 11.3%-36.5%; P = .02). Infection prevention was not compromised, because the incidence of central line-associated bloodstream infections was 27.6% in the alcohol cohort vs 27.3% in the acetate cohort (P = .98). Our results demonstrated that using 0.2% CHG acetate and not 0.5% CHG-70% alcohol as a skin disinfectant in extremely preterm infants results in fewer chemical burns, without increasing the risk of central line-associated bloodstream infections. The use of 0.2% CHG acetate could be considered as an option for skin disinfection in extremely preterm infants.