Simultaneous Isolated Bilateral Superior Orbital Vein Thrombosis as a Presenting Feature of Antiphospholipid Syndrome

Abstract

Although superior ophthalmic vein occlusion is rare, it is an important differential as orbital biopsy is to be avoided. This is only the second reported case secondary to antiphospholipid syndrome and the first such case with bilateral occlusions.

Superior Ophthalmic Vein Thrombosis with Cerebral Venous Sinus Thrombosis: A Rare Entity in a Child

“…[12][13][14][15][16] Other causes are hematologic like antiphospholipid syndrome, sickle cell disease, hormonal causes like tamoxifen, oral contraceptive pills etc, Tolosa-Hunt syndrome, idiopathic orbital inflammatory disease. [17][18][19][20][21][22][23][24][25] In a case series by Nicolien et al 3 the majority of the patients were aseptic (seven out of nine) although all the patients in this case series were adults. The septic causes were sinusitis, dental, orbital and facial infection.…”

Impact of superior ophthalmic vein thrombosis: a case series and literature review

“…[9][10][11][12][13] Hematologic aetiologies include antiphospholipid syndrome and sickle trait. [14][15][16][17] Also, hormone therapies have been reported as a cause for SOVT (e.g. tamoxifen, oral contraceptive pill).…”

Bilateral isolated concurrent superior ophthalmic vein thrombosis in systemic lupus erythematosus

“…There is a report of a female who developed bilateral SOVT 6 with associated peripheral retinal hemorrhages, on oral contraceptive pills. Idrees et al, 7 reported recently a case of bilateral SOV thrombosis secondary to antiphospholipid syndrome in a female with good vision along with associated disc swelling and proptosis. Our patient had good vision on presentation, with minimal orbital congestive signs; BCVA improved to 20/20 after treatment with anticoagulation and steroids.…”