Simultaneous Optimization of Microwave-Assisted Extraction of Phenolic Compounds and Antioxidant Activity of Avocado (<i>Persea americana</i> Mill.) Seeds Using Response Surface Methodology

Weremfo, Alexander; Adulley, Felix; Adarkwah-Yiadom, Martin

doi:10.1155/2020/7541927

Cited by 65 publications

(44 citation statements)

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“…In the literature, there are two types of mathematical models dedicated to microwave extraction: theoretical models based on chemical engineering principles about solid–liquid diffusion [ 39 , 40 , 41 , 42 ] and empirical statistical models based mostly on Response Surface Methodology (RSM) [ 17 , 31 , 43 , 44 , 45 ] but also on Adaptive Neuro-Fuzzy Inference System (ANFIS) statistical methodology [ 46 , 47 ].…”

Section: Discussionmentioning

confidence: 99%

Optimization of Vacuum-Microwave-Assisted Extraction of Natural Polyphenols and Flavonoids from Raw Solid Waste of the Orange Juice Producing Industry at Industrial Scale

et al. 2021

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Orange pomace (OP) is a solid waste produced in bulk as a byproduct of the orange juice industry and accounts for approximately 50% of the quantity of the fruits processed into juice. In numerous literature references there is information about diverse uses of orange pomace for the production of high-added-value products including production of natural antioxidant and antimicrobial extracts rich in polyphenols and flavonoids which can substitute the hazardous chemical antioxidants/antimicrobials used in agro-food and cosmetics sectors. In this work and for the first time, according to our knowledge, the eco-friendly aqueous vacuum microwave assisted extraction of orange pomace was investigated and optimized at real industrial scale in order to produce aqueous antioxidant/antimicrobial extracts. A Response Surface Optimization methodology with a multipoint historical data experimental design was employed to obtain the optimal values of the process parameters in order to achieve the maximum rates of extraction of OP total polyphenols and/or total flavonoids for economically optimum production at industrial scale. The three factors used for the optimization were: (a) microwave power (b) water to raw pomace ratio and (c) extraction time. Moreover, the effectiveness and statistical soundness of the derived cubic polynomial predictive models were verified by ANOVA.

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Section: Discussionmentioning

confidence: 99%

Optimization of Vacuum-Microwave-Assisted Extraction of Natural Polyphenols and Flavonoids from Raw Solid Waste of the Orange Juice Producing Industry at Industrial Scale

et al. 2021

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“…Concerning the technology, some authors have investigated the feasibility of microwave-assisted extraction [82,83] and accelerated solvent extraction [84] as thermal-type extractions, and ultra-sound assisted extraction [79,83] and supercritical CO 2 extraction (with ethanol as co-solvent) [85] as non-thermal procedures ( Table 5). These techniques require shorter processing times, less energy, and considerably lower amounts of chemicals or solvents.…”

Section: Phenolic Compoundsmentioning

confidence: 99%

“…Among them, supercritical CO 2 extraction and microwave-assisted extraction seem to have a higher efficiency to solubilize the phenolic compounds from the peel and stone, while the highest purity of the extracts were reached using Soxhlet extraction with water for the peel and microwave-assisted extraction with 70% acetone for the stone. The latter is characterized to be a fast and efficient extraction method due to the rapid heat generation by the microwaves energy, which causes destruction of the cellular matrix to release phenolic compounds, with extraction times lower than 20 min [82,83]. Furthermore, in a recent work, another strategy was followed to recover phenolic compounds from the pomace part, i.e., using aqueous two-phase systems, based on two immiscible liquid phases.…”

Section: Phenolic Compoundsmentioning

confidence: 99%

“…Thus, water, aqueous-ethanolic solutions, and CO 2 as solvents could be some options. For example, Weremfo et al [83] have shown that microwave-assisted extraction (400 W) with 58% ethanol can be applied to obtain phenolic compounds from avocado stone in a short time (4.8 min). This enables the recovery of an even higher TPC than using ultrasound-assisted extraction.…”

Section: Phenolic Compoundsmentioning

confidence: 99%

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Avocado-Derived Biomass as a Source of Bioenergy and Bioproducts

2020

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The avocado (Persea americana Mill.) is a tree native to Mexico and Guatemala. Avocado consumption, fresh or in the form of processed products, is growing everywhere and it has caused a large number of countries to invest heavily in avocado production. The industrialization of avocado gives as a result a huge amount of waste, not only the peel and stone but also that waste generated by the pruning practices and oil extraction. These biomasses could be converted into raw materials to obtain different types of co-products, but this implies changes in the use of these resources, the design of efficient production systems, and integration to take full advantage of them, e.g., by developing biorefinery models. Therefore, this review firstly gives a snapshot of those residues generated in the avocado industry and provides their chemical composition. Secondly, this review presents updated information about the valorization ways of avocado-derived biomass to obtain bioenergy, biofuels, and other marketable products (starch, protein, phenolic compounds, and biosorbents, among others) using a single process or integrated processes within a biorefinery context. Green technologies to obtain these products are also covered, e.g., based on the application of microwaves, ultrasound, supercritical fluids, etc. As a conclusion, there is a variety of ways to valorize avocado waste in single processes, but it would be promising to develop biorefinery schemes. This would enable the avocado sector to move towards the zero-waste principle.

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“…RSM is an accurate and efficient optimization method widely used in various fields, including food processing, chemistry, biology, and agriculture [ 14 , 15 , 16 ]. Over the past decades, the interest in pharmaceuticals, cosmetics, and functional foods containing natural products has increased; consequently, there is ongoing research in both academia and industry aimed at developing such products [ 17 , 18 ]. The first step in these studies involves extraction of the bioactive constituent from natural products.…”

Section: Introductionmentioning

confidence: 99%

Characterization and Optimization of the Tyrosinase Inhibitory Activity of Vitis amurensis Root Using LC-Q-TOF-MS Coupled with a Bioassay and Response Surface Methodology

Shin

Lee

et al. 2021

Molecules

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Vitis amurensis roots have been reported to have the potential for skin whitening through the evaluation of melanogenesis and tyrosinase inhibitory activities. In this study, V. amurensis roots were utilized to quickly select whitening ingredients using LC-Q-TOF-MS coupled with tyrosinase inhibitory assay, and to optimize the extraction process for use as a skin whitening functional material by response surface methodology. Results showed that V. amurensis roots exhibited tyrosinase inhibitory effects by two stilbene oligomers, ε-viniferin (1) and vitisin B (2), as predicted by LC-Q-TOF-MS coupled with bioassay. The optimal extraction conditions (methanol concentration 66%, solvent volume 140 mL, and extraction time 100 min) for skin whitening ingredients were established with the yields 6.20%, and tyrosinase inhibitory activity was 87.27%. The relationship between each factor and its corresponding response was confirmed by Pearson’s correlation analysis. The solvent volume showed clear linear relationship with yields, and methanol concentration had a strong linear relationship with tyrosinase inhibitory activity for compounds 1 and 2, as well as their combination. Overall, LC-Q-TOF-MS coupled with bioassay was proved to have the potential to effectively find new active constituents, as well as known active constituents; vitisin B can be proposed as a new natural potential whitening agent.

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Simultaneous Optimization of Microwave-Assisted Extraction of Phenolic Compounds and Antioxidant Activity of Avocado (Persea americana Mill.) Seeds Using Response Surface Methodology

Cited by 65 publications

References 50 publications

Optimization of Vacuum-Microwave-Assisted Extraction of Natural Polyphenols and Flavonoids from Raw Solid Waste of the Orange Juice Producing Industry at Industrial Scale

Optimization of Vacuum-Microwave-Assisted Extraction of Natural Polyphenols and Flavonoids from Raw Solid Waste of the Orange Juice Producing Industry at Industrial Scale

Avocado-Derived Biomass as a Source of Bioenergy and Bioproducts

Characterization and Optimization of the Tyrosinase Inhibitory Activity of Vitis amurensis Root Using LC-Q-TOF-MS Coupled with a Bioassay and Response Surface Methodology

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