2005
DOI: 10.1016/j.jpba.2005.02.007
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Simultaneous quantification of atomoxetine as well as its primary oxidative and O-glucuronide metabolites in human plasma and urine using liquid chromatography tandem mass spectrometry (LC/MS/MS)

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Cited by 36 publications
(30 citation statements)
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“…Table 3 The accuracy, within-and between-batch precision and recovery data for the measurement of atomoxetine in human plasma All stability results are summarized in Table 4. These results are in agreement with atomoxetine stability in plasma as previously reported by Mullen and co-workers [18].…”
Section: Stabilitysupporting
confidence: 93%
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“…Table 3 The accuracy, within-and between-batch precision and recovery data for the measurement of atomoxetine in human plasma All stability results are summarized in Table 4. These results are in agreement with atomoxetine stability in plasma as previously reported by Mullen and co-workers [18].…”
Section: Stabilitysupporting
confidence: 93%
“…Both solid phase extraction (SPE) and liquid-liquid extraction (LLE) sample preparation methods have been reported [15,[18][19][20]. The SPE method used polystyrenedivinylbenzene to extract atomoxetine from plasma and urine [18]. For routine clinical analysis, a high-throughput method with SPE carries higher cost than LLE.…”
Section: Discussionmentioning
confidence: 99%
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“…The reported methods for the determination of atomoxetine include expensive liquid chromatography tandem mass spectrometry (LCMS) or HPLC with liquid scintillation counting (LSC) detection [9][10][11]. No method has been reported so far for determination of atomoxetine using HPLC with UV detection.…”
Section: Introductionmentioning
confidence: 99%