Single Center Experience With 250 Tunnelled Pleural Catheter Insertions for Malignant Pleural Effusion

Management of Pleural Effusion by Combining Talc Poudrage and Indwelling Pleural Catheter: A Retrospective Single Center Study

“…The probability of spontaneous pleurodesis with an IPC insertion without additional talc poudrage lies between 26% and 76% [6,8,13]. The goal of regular drainage of IPC is symptom relief and promoting spontaneous pleurodesis by keeping the intrapleural space dry [6]. The IPC was designed to be left in situ for the remaining lifespan of the patient.…”

“…Today, talc pleurodesis is a safe procedure and talc is known to be the most successful pleurodesis agent with a success rate of more than 70% [3][4][5]. A major disadvantage of the procedure is however the need of chest tube(s) and the therefore long hospital stay up to seven days until they can be removed [6].…”

“…Intermittent fluid drainage is needed until efficient pleurodesis occurs [6]. The use of IPCs improves the quality of life in patients [7].…”

Managing malignant pleural effusion with an indwelling pleural catheter: factors associated with spontaneous pleurodesis

“…The pooled rate of SP in MPE patients has been reported to be 45.6%, 11 achieved after a mean duration of 26 to 56 days after IPC insertion. [11][12][13][14][15][16][17][18][19][20] The possibility of SP is attractive as there is a chance that an IPC will no longer be required. The aims of this study were to review our single-centre experience of the safety of IPC in the management of symptomatic MPE and to explore the potential clinical factors associated with SP.…”

Derrame pleural neoplásico

“…Este processo pressupõe aposição das pleuras visceral e parietal, mediante drenagem de todo o líquido acumulado e reexpansão pulmonar. (1,3,(6)(7)(18)(19) O resultado da pleurodese é melhor alcançado quando alguns pré-requisitos básicos são obedecidos (Quadro 1). (1,3,(6)(7)19) Os agentes indutores de pleurodese mais freqüentemente usados podem ser de natureza citotóxica, como os antineoplásicos (bleomicina), agentes cáusticos (nitrato de prata), antibióticos (tetraciclina e seus derivados doxiciclina e minociclina) e o talco, que pode ser usado em aerossol (polvilhamento) ou em suspensão em soro fisiológico.…”