Single-lung transplantation: does side matter?

Tsagkaropoulos, Sokratis; Belmans, Ann; Verleden, Geert M.; Coosemans, Willy; Decaluwé, Herbert; Leyn, Paul De; Nafteux, Philippe; Raemdonck, Dirk Van

doi:10.1016/j.ejcts.2011.03.011

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…In contrast to SSLTx, SLT recipients are more likely to experience pneumothorax, hyperinflation, and opportunistic infections, especially with Mycobacterium species and Aspergillus associated with native lung. Therefore, this can potentially compromise both early and late outcomes[ 58 , 60 ].…”

Section: Native Lung Complicationsmentioning

confidence: 99%

Factors affecting complications development and mortality after single lung transplant

Sekulovski¹,

Simonska²,

Peruhova³

et al. 2021

WJT

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Lung transplantation (LT) is a life-saving therapeutic procedure that prolongs survival in patients with end-stage lung disease. Furthermore, as a therapeutic option for high-risk candidates, single LT (SLT) can be feasible because the immediate morbidity and mortality after transplantation are lower compared to sequential single (double) LT (SSLTx). Still, the long-term overall survival is, in general, better for SSLTx. Despite the great success over the years, the early post-SLT period remains a perilous time for these patients. Patients who undergo SLT are predisposed to evolving early or late postoperative complications. This review emphasizes factors leading to post-SLT complications in the early and late periods including primary graft dysfunction and chronic lung allograft dysfunction, native lung complications, anastomosis complications, infections, cardiovascular, gastrointestinal, renal, and metabolite complications, and their association with morbidity and mortality in these patients. Furthermore, we discuss the incidence of malignancy after SLT and their correlation with immunosuppression therapy.

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Section: Native Lung Complicationsmentioning

confidence: 99%

Factors affecting complications development and mortality after single lung transplant

Sekulovski¹,

Simonska²,

Peruhova³

et al. 2021

WJT

View full text Add to dashboard Cite

show abstract

“…Since the native lung on the severe side is more dysfunctional, it would not be unreasonable to choose that side for transplantation. However, Tsagkaropoulos et al reported that the transplant side does not influence recipient survival, freedom from bronchiolitis obliterans, complications, or pulmonary function after SLT [ 83 ]. Besides surgical considerations in the recipient, the offer of a donor lung opposite to the preferred side should not be a reason to postpone the transplantation until a better-matched donor is found [ 83 ].…”

Section: Size Matchingmentioning

confidence: 99%