2018
DOI: 10.4172/2153-0645.1000178
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Single Nucleotide Polymorphisms as Biomarkers for Drug Response and Toxicity in the Management of Colorectal Cancer

Abstract: The current methods of cancer treatment don't focus on the influence of interpatient genetic variations on the treatment outcomes. Genetic variations in the genes which are involved with drug metabolism and targets can affect treatment response and toxicity. In the recent time, many advances have been made to detect such candidate gene variations and use them as biomarkers in predicting the treatment outcomes in colorectal cancer (CRC). CRC remains one of the common causes of worldwide morbidity and mortality.… Show more

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