Single nucleotide polymorphisms in the cannabinoid CB2 receptor: Molecular pharmacology and disease associations
Tahira Foyzun,
Maddie Whiting,
Kate K. Velasco
et al.
Abstract:Preclinical evidence implicating cannabinoid receptor 2 (CB2) in various diseases has led researchers to question whether CB2 genetics influence aetiology or progression. Associations between conditions and genetic loci are often studied via single nucleotide polymorphism (SNP) prevalence in case versus control populations. In the CNR2 coding exon, ~36 SNPs have high overall population prevalence (minor allele frequencies [MAF] ~37%), including non‐synonymous SNP (ns‐SNP) rs2501432 encoding CB2 63Q/R. Interspe… Show more
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