Single versus biplane right and left ventricular volumetry: A cast and clinical study

Abstract

True volume (y) and measured volume (x) determined from 23 right and 22 left normal human casts in four biplane angiographic positions and in their eight single-plane components were used to find the correction factor (b) by regression through the origin (y = bx). The correction factors were applied to human studies to assess the validity of the various biplane and single-plane modalities in vivo. The casts studies yield excellent correlations in both right and left biplane methods (right volumetry: 0.555 less than or equal to b less than or equal to 0.708, 0.917 less than or equal to r less than or equal to 0.954, 4.10 less than or equal to SEE less than or equal to 6.01 left volumetry: 0.748 less than or equal to b less than or equal to 0.825, 0.974 less than or equal to r less than or equal to 0.982, 4.81 less than or equal to SEE 5.79). Good results were obtained with single-plane volumetries as well (right volumetry: 0.316 less than or equal to b less than or equal to 0.887, 0.750 less than or equal to r less than or equal to 0.917, 10.75 less than or equal to SEE less than or equal to 18.96; left volumetry: 0.728 less than or equal to b less than or equal to 0.881, 0.897 less than or equal to r less than or equal to 0.976 5.73 less than or equal to SEE less than or equal to 11.97). The correction factors for the single-plane studies depend much more strongly on the spatial position relative to the radiographic system, particularly in the case of the right ventricular volumes. Thus, the application of the appropriate correction factors is mandatory. The human studies (141 left and 60 right volumetric studies in various single-plane and biplane projections) showed a larger scatter of single-plane values, more pronounced for the right ventricle. In certain disease conditions, single plane volumetric studies using cast-derived correction factors cannot be used to obtain meaningful results. Correction factors for the following single or biplane mode volumetry are presented for the first time: biplane hepatoclavicular view (right and left ventricle), biplane long axial oblique view (right ventricle), and their single-plane components; lateral and 60 degree Left Anterior Oblique (LAO) single plane for the left-sided measurements, Postero-Anterior (PA), lateral, and 60 degree LAO for the single-plane right-sided calculations.

The Conductance Volume Catheter Technique for Measurement of Left Ventricular Volume in Young Piglets

“…Although left ventricular angiocardiography is an accepted method of measurement of time-varying left ventricular volume, it requires human judgment (1 8) and is very time-consuming (1 8-20), even with the use of an image quantification computer. Variability is noted in the studies validating angiocardiography as a technique for volume measurement (18,21,22), and it frequently overestimates true volume (1 8, 2 1-24). More importantly, angiocardiography alters the loading conditions and contractile function of the ventricle (25).…”

Quantitative validation of cineangiographic axial oblique biplane left ventricular volume measurement

“…The first study by Formanek et a1 used 22 human LV casts, arbitrarily devided into 13 enddiastolic and 9 end-systolic casts, range 15.2 to 114.8 ml [3]. The casts were studied in conventional biplane PA/ Lat and 30"RA0/60°LA0 views and compared to nonorthogonal biplane 70"RA0/45"LA0/35"-40"Cr and 60"RA0/60"LA0/25"-30"Cr views.…”