Sinonasal Tumors

Sen, Saugata; Chandra, Aditi; Mukhopadhyay, Sumit; Ghosh, P. K.

doi:10.1016/j.nic.2015.07.006

Cited by 17 publications

(1 citation statement)

References 52 publications

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“…However, its diagnostic sensitivity is low because of the surrounding inflammatory tissue, which usually accompanies the biopsy specimen. CT and MRI imaging play a crucial role in the differentiation of sinonasal tumors (11)(12)(13). However, the image morphologies of malignant and benign sinonasal neoplasms often overlap, and are nonspecific (12,14,15).…”

Section: Introductionmentioning

confidence: 99%

Radiomics Nomograms Based on Multi-Parametric MRI for Preoperative Differential Diagnosis of Malignant and Benign Sinonasal Tumors: A Two-Centre Study

Zhang

Wang

et al. 2021

Front. Oncol.

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ObjectivesTo investigate the efficacy of multi-parametric MRI-based radiomics nomograms for preoperative distinction between benign and malignant sinonasal tumors.MethodsData of 244 patients with sinonasal tumor (training set, n=192; test set, n=52) who had undergone pre-contrast MRI, and 101 patients who underwent post-contrast MRI (training set, n=74; test set, n=27) were retrospectively analyzed. Independent predictors of malignancy were identified and their performance were evaluated. Seven radiomics signatures (RSs) using maximum relevance minimum redundancy (mRMR), and the least absolute shrinkage selection operator (LASSO) algorithm were established. The radiomics nomograms, comprising the clinical model and the RS algorithms were built: one based on pre-contrast MRI (RNWOC); the other based on pre-contrast and post-contrast MRI (RNWC). The performances of the models were evaluated with area under the curve (AUC), calibration, and decision curve analysis (DCA) respectively.ResultsThe efficacy of the clinical model (AUC=0.81) of RNWC was higher than that of the model (AUC=0.76) of RNWOC in the test set. There was no significant difference in the AUC of radiomic algorithms in the test set. The RS-T1T2 (AUC=0.74) and RS-T1T2T1C (RSWC, AUC=0.81) achieved a good distinction efficacy in the test set. The RNWC and the RNWOC showed excellent distinction (AUC=0.89 and 0.82 respectively) in the test set. The DCA of the nomograms showed better clinical usefulness than the clinical models and radiomics signatures.ConclusionsThe radiomics nomograms combining the clinical model and RS can be accurately, safely and efficiently used to distinguish between benign and malignant sinonasal tumors.

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Section: Introductionmentioning

confidence: 99%

Radiomics Nomograms Based on Multi-Parametric MRI for Preoperative Differential Diagnosis of Malignant and Benign Sinonasal Tumors: A Two-Centre Study

Zhang

Wang

et al. 2021

Front. Oncol.

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Management of post‐implant fibrous dysplasia in the maxilla: A case study

Amrou,

Koleilat,

Alrmali

et al. 2024

Clin Adv Periodontics

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BackgroundFibrous dysplasia is generally rare, and even rarer in older adults. Special care is needed when altering the alveolar bone in these cases, especially if an implant is involved. This case study highlights such a scenario.MethodsThis case study details the experience of a 63‐year‐old African American female who presented with a bump on her jaw, ultimately leading to a diagnosis of fibrous dysplasia. The patient underwent surgery for osseous recontouring to address the bone overgrowth associated with the condition.ResultsThe study documents the successful surgical recontouring of a fibrous dysplasia lesion in the upper right maxilla that developed 5 years after dental implant placement. Additionally, it highlights the preservation of peri‐implant hard and soft tissues over a 6‐month follow‐up period post‐surgery, ensuring proper tissue healing and bone shaping for optimal patient outcomes.ConclusionThe successful surgical recontouring of fibrous dysplasia in the upper right maxilla, along with the preservation of peri‐implant hard and soft tissues, underscores the potential for effective oral rehabilitation in similar cases involving dental implants.Plain Language SummaryIn this study, we managed a rare bone disorder called fibrous dysplasia in a 63‐year‐old woman, 5 years after she had dental implants in her upper jaw. This condition leads to bone overgrowth and deformities, making oral rehabilitation challenging. The patient presented with a bump in her upper jaw, which was diagnosed through various tests. We performed surgery to reshape the overgrown bone while preserving her dental implants and surrounding tissues. The surgery was successful, and 6 months later, the implants remained stable with no signs of recurring issues.Key pointsWhy is this case new information?This case is rare because it presents a successful management strategy for fibrous dysplasia in the maxilla with dental implants, a combination that is both uncommon and challenging.What are the keys to the successful management of this case?Successful management relies on accurate diagnosis, careful surgical recontouring to preserve peri‐implant bone while providing a maintainable environment for the patient, and thorough postoperative care to ensure healing and stability.What are the primary limitations to success in this case?Primary limitations include the risk of implant compromise, potential recurrence of fibrous dysplasia, and challenges related to bone quality and healing, particularly in an older patient.

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