Background: Psoriasis is a chronic inflammatory, immune-mediated systemic disease with skin manifestations that typically follow a relapsing and remitting course. The most common form, plaque psoriasis, occurs in ∼80-90% of psoriatic patients. Objective: The aim of the current work was to evaluate level of serum testosterone in psoriasis male patients and its relation to severity of the disease. Patients and methods: This cohort study included a total of 35 psoriatic patients, attending At Outpatient Clinic,