Skin manifestations of Bartonella infections

Chián, César; Arrese, Jorge E.; Pierard, Gérald

doi:10.1046/j.1365-4362.2002.01489.x

Cited by 57 publications

(40 citation statements)

References 49 publications

(51 reference statements)

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“…Maintenance of these peculiar tumors is fully dependent on the presence of live bacteria, since eradication of the pathogen by antibiotic treatment is known to efficiently resolve the lesions (365). The striking similarity of clinical and histological features and the strong association of both bacillary angiomatosis and verruga peruana with preceding immunosuppression generated the hypothesis that these conditions may be caused by similar means of molecular pathogenesis (86).…”

Section: The Primary Nichementioning

confidence: 99%

Intruders below the Radar: Molecular Pathogenesis of Bartonella spp

2012

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SUMMARY Bartonella spp. are facultative intracellular pathogens that employ a unique stealth infection strategy comprising immune evasion and modulation, intimate interaction with nucleated cells, and intraerythrocytic persistence. Infections with Bartonella are ubiquitous among mammals, and many species can infect humans either as their natural host or incidentally as zoonotic pathogens. Upon inoculation into a naive host, the bartonellae first colonize a primary niche that is widely accepted to involve the manipulation of nucleated host cells, e.g., in the microvasculature. Consistently, in vitro research showed that Bartonella harbors an ample arsenal of virulence factors to modulate the response of such cells, gain entrance, and establish an intracellular niche. Subsequently, the bacteria are seeded into the bloodstream where they invade erythrocytes and give rise to a typically asymptomatic intraerythrocytic bacteremia. While this course of infection is characteristic for natural hosts, zoonotic infections or the infection of immunocompromised patients may alter the path of Bartonella and result in considerable morbidity. In this review we compile current knowledge on the molecular processes underlying both the infection strategy and pathogenesis of Bartonella and discuss their connection to the clinical presentation of human patients, which ranges from minor complaints to life-threatening disease.

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Section: The Primary Nichementioning

confidence: 99%

Intruders below the Radar: Molecular Pathogenesis of Bartonella spp

2012

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“…5 One week after inoculation by a cat scratch or bite an erythematous papule that appears at the puncture site persists for 1 to 3 weeks. 6 Regional lymphadenopathy develops 1-3 weeks after inoculation. Eighty five percent of patients have single lymph node involved and systemic lymphadenopathy is exceptional.…”

Section: Discussionmentioning

confidence: 99%

Cat Scratch Disease

Bhattacharjee¹,

Bhattacharjee²,

Montasir³

2012

J Enam Med Col

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“…In einigen Fällen wurden auch B. clarridgeiae und Afipia felis beschrieben [1]. Die Erreger werden durch Kratz oder Bissverletzungen v. a. von jungen Katzen übertragen [2].…”

Section: Kommentarunclassified

“…Nach 1-7 Wochen werden die Lymph knoten im entsprechenden Drainagege biet befallen [1]. Bei der Differenzialdiag nose der Lymphknotenschwellung müs sen infektiöse, maligne, lymphoprolifera tive, immunologische sowie Stoffwech selerkrankungen ausgeschlossen wer den.…”

Section: Kommentarunclassified

Katzenkratzkrankheit

Felbert

Meybehm²,

Megahed

2008

Hautarzt

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Interessenkonflikt. Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht. Literatur 1. Cunliffe WJ, Baron SE, Coulson IH (2001) A clinical and therapeutic study of 29 patients with infantile acne. Br J Dermatol 145: 463-466 2. Janniger CK (1993) Neonatal and infantile acne vulgaris. Cutis 52: 16 3. Jansen T, Burgdorf WH, Plewig G (1997) Pathogenesis and treatment of acne in childhood. Pediatr Dermatol 14: 17-21 4. Herane MI, Ando I (2003) Acne in infancy and acne genetics. Dermatology 206: 24-28 5. Harde V, Muller M, Sippell WG et al. (2006) Acne infantum as presenting symptom of congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. J Dtsch Dermatol Ges 4: 654-657 6. Tabata N, Terui T, Watanabe M, Tagami H (1995) Infantile acne associated with a high plasma testosterone level in a 21-month-old boy. J Am Acad Dermatol 33: 676-678 7. Lucky AW (1998) A review of infantile and pediatric acne. Dermatology 196: 95-97 8. Torrelo A, Pastor MA, Zambrano A (2005) Severe acne infantum successfully treated with isotretinoin. Pediatr Dermatol 22: 357-359 9. Barnes CJ, Eichenfield LF, Lee J, Cunningham BB (2005) A practical approach for the use of oral isotretinoin for infantile acne. Pediatr. Dermatol 22: 166-169 10. Arbegast KD, Braddock SW, Lamberty LF, Sawka AR (1991) Treatment of infantile cystic acne with oral isotretinoin: a case report.

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Skin manifestations of Bartonella infections

Cited by 57 publications

References 49 publications

Intruders below the Radar: Molecular Pathogenesis of Bartonella spp

Intruders below the Radar: Molecular Pathogenesis of Bartonella spp

Cat Scratch Disease

Katzenkratzkrankheit

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