Sleep Apnea -- A Major Public Health Problem

Phillipson, Eliot A.

doi:10.1056/nejm199304293281712

Cited by 357 publications

(175 citation statements)

References 16 publications

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“…20 A rapid development of sleep laboratories occurred in the 1980s largely as a result of the availability of therapeutic alternatives to tracheostomy and the commercial availability of CPAP (circa 1983), an improvement on the initial application of the technique that required custom masks and industrial blowers. 21 As better described in other historical reviews, in the 1990s there occurred a rapid expansion in private and academic sleep programs when it became evident that obstructive sleep apnea syndrome was a significant public health problem, 22 and noninvasive ventilation as well as positive pressure therapy became accepted treatment. The clinical interest in sleep disorders grew rapidly and independently.…”

Section: History Of the Clinical Fieldmentioning

confidence: 99%

Sleep Medicine Training Across the Spectrum

Strohl

2011

Chest

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Section: History Of the Clinical Fieldmentioning

confidence: 99%

Sleep Medicine Training Across the Spectrum

Strohl

2011

Chest

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“…It has thus become a public health issue. [6][7][8][9] Obesity itself is fast becoming a pandemic. 10 The World Health Organization classifies obesity based on the bodymass index (BMI), which is weight (in kilograms) divided by the square of the height (in meters).…”

Section: Introductionmentioning

confidence: 99%

Achados clínicos e polissonográficos em pacientes com obesidade classe III

Tangerina¹,

Martinho²,

Togeiro

et al. 2008

Rev. Bras. Otorrinolaringol.

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The Obstructive Sleep Apnea/Hipopnea Syndrome (OSAHS) is closely related to obesity; a linear relation, however, has not been established, particularly in morbid obesity patients. Aim: To evaluate clinical and polysomnographic findings in a group of class III obese patients, and to relate these findings with the presence or absence of OSAHS. Material and Method: Forty five patients with body mass indexex (BMI) over 40Kg/m2 were selected consecutively. A clinical history, the anthropometric examination and polysomnography were undertaken in all patients. The results of a study group and a control group (with no OSAHS) were compared. Results: The sample consisted of 68.9% female and 31.1% male patients. The average age was 46.5 years (SD -10.8 years); the average BMI was 49 (SD -7 Kg/m2) and the average neck circumference was 43.4 cm (SD -5.1 cm). All subjects were habitual snorers and 48.9% had daytime drowsiness. Polysomnography showed that 77.8% had an apnea/hipopnea index over 5. The findings associated with OSAHS were: younger age (p=0,02) and an increased neck circumference (p=0.004). Conclusion: The prevalence of OSAHS was very high, which emphasizes the importance of investigating this syndrome in patients sent for bariatric surgery. The neck circumference was the best OSAHS marked in this group of patients.

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“…In addition, sleep-related breathing disorder is a potential risk factor for cardiovascular disease (24)(25)(26)(27). Shamsuzzaman et al (28) completed a systematic review regarding the interactions of OSA with cardiovascular pathophysiology and disease.…”

Section: Discussionmentioning

confidence: 99%

Cardiomyopathy Presenting as Severe Fatigue in a Person With Chronic Spinal Cord Injury

Kam

Sankaran²,

Gowda³

et al. 2009

The Journal of Spinal Cord Medicine

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Background/Objective: To describe a case of fatigue associated with cardiomyopathy in a man with spinal cord injury. Study Design: Case report. Subject: An obese 35-year-old man with long-term ASIA A L2 paraplegia, accompanied by a 2-year history of progressive severe fatigue. Methods: Physical examination showed obesity, hypertension, tachycardia, and pitting edema. An echocardiogram showed a 20% ejection fraction, severe dilation, and global hypokinesis in the left ventricle and mild to moderate mitral regurgitation. Results: Symptoms improved after treatment with furosemide, warfarin, ramipril, and continuous positive airway pressure for obstructive sleep apnea. Conclusion: Severe progressive fatigue in a patient with chronic SCI may signal cardiomyopathy. Diagnostic studies may be warranted in patients with progressive fatigue.

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Sleep Apnea -- A Major Public Health Problem

Cited by 357 publications

References 16 publications

Sleep Medicine Training Across the Spectrum

Sleep Medicine Training Across the Spectrum

Achados clínicos e polissonográficos em pacientes com obesidade classe III

Cardiomyopathy Presenting as Severe Fatigue in a Person With Chronic Spinal Cord Injury

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