Sleep apnea in patients with hemispheric stroke

Sleep Apnea and Cardiovascular Disease

“…Dyken et al 218 noted that patients after stroke have a high prevalence of OSA and that those stroke patients with OSA had a markedly diminished poststroke survival. Similar findings regarding survival and limited rehabilitation success 219,220 have been reported by other investigators. Direct studies of the interaction between sleep apnea and rehabilitation outcome after stroke that used overnight pulse oximetry to evaluate the respiratory disturbance index suggested that hypoxic events during sleep predicted poorer recovery, especially in patients with poor function at admission.…”

“…220 The site of brain lesion, magnitude of injury, effects on upper airway tone, effects of supine posture during polysomnography, consequences of transient mental obtundation, and medications may have striking effects on the presence and severity of sleep apnea. The prevalence of sleep apnea several months after stroke, although still high, is less than that evident in the acute poststroke phase.…”

Diagnosis and Treatment of Sleep Apnea in Patients' Homes: The Rationale and Methods of the “GoToSleep” Randomized-Controlled Trial

“…[2][3][4][5][6][7][8][9][10] Sleep apnea has been independently associated with a variety of adverse metabolic and disease states and outcomes including hypertension, diabetes, stroke and TIA, incident coronary events and cardiovascular mortality, and all-cause mortality. 1,4,[11][12][13] Unfortunately, estimates suggest that as many as 70% to 80% of patients with sleep apnea are neither diagnosed nor treated.…”

“…Most studies in this area have reported that 60% to 70% of patients with stroke or TIA have sleep apnea. [2][3][4][5][6][7][8][9][10]13,44 Therefore, in the GoToSleep study, patients with cerebrovascular disease were included on the basis of their high pre-test probability of having sleep apnea. No additional clinical characteristic (e.g., daytime sleepiness) were used as part of the inclusion criteria because we sought to include both patients who are symptomatic and patients who are asymptomatic but who nonetheless experience the physiologic consequences of their sleep related respiratory events.…”

Sleep related breathing disorders and cerebrovascular diseases

“…OSAS'da hipoksi, hiperkapni varlığı ve torasik gerilim reseptörlerinden azalan input etkilerine bağlı olarak gelişen refleks sonucu sempatik sinir sistem Türk Serebrovasküler Hastalıklar Dergisi 2010 16:1; 1-6 olguların %71'inde OSAS saptanmıştır (58).…”