“…102−106 In addition, large stress gradients along the radius drove the cracks so quickly that there was little chance to trigger microscale toughening mechanisms resulting from tablet sliding. 13,56,87,88 While excellent work has been achieved using in situ SEM or TEM to probe the mechanical properties of individual tablets, research on the intertablet properties is limited, maybe because it is difficult to handle the tiny intertablet space and preserve the original microstructures of nacre. 107 Furthermore, it will trigger the tablet sliding mechanisms in mode II condition such as in tension, compression, bending, or direct shear.…”