Small airway dysfunction in chronic hypersensitivity pneumonitis

Zúñiga, Selene Guerrero; Hernandez, J.; Toledo, Heidegger Mateos; Ávila, Mayra Mejía; Gochicoa‐Rangel, Laura; Reyes, José Luis Miguel; Selman, Moisés; Torre-Bouscoulet, Luis

doi:10.1111/resp.13124

Cited by 16 publications

(10 citation statements)

References 33 publications

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“…IOS was obtained, and it did show elevated AX at baseline and improved with treatment particularly with azathioprine and prednisone. It is noted that lung volume also improved but not gas exchange [24].…”

Section: Ios and Other Respiratory Conditionsmentioning

confidence: 95%

Clinical Applications of Impulse Oscillometry

Saadeh¹,

Davey-Ranasinghe²

2019

Asthma - Biological Evidences

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Impulse oscillometry is a noninvasive procedure that can be performed within few minutes. The purpose of the procedure is to measure the resistance of the small and large airways, as well as the reactants of the airways. It is gradually gaining popularity in evaluating lung function, particularly in patients with asthma and COPD. In contrast to spirometry, the test performs measurement during tidal breathing. In other words, forced exhalation is not required. Other advantages include, but are not limited to, evaluating COPD patients' reversibility which is rarely noted on spirometry. IOS also is tool for chronic management of patients with asthma and COPD while on treatment. It can evaluate children with asthma even as young as 2 years old. Spirometry requires the child to cooperate and usually is of meaningful use beginning at the age of 5 years old. Other potential applications include early evaluation of transplant rejection, cystic fibrosis, and vocal cord disorder. In this chapter, we will explore the procedure itself, the settings, advantages and disadvantages, and comparative data with spirometry.

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Section: Ios and Other Respiratory Conditionsmentioning

confidence: 95%

Clinical Applications of Impulse Oscillometry

Saadeh¹,

Davey-Ranasinghe²

2019

Asthma - Biological Evidences

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“…Radiological characteristics that may be observed at HRCT include mosaic pattern indicating air trapping and bronchial wall thickening. Other non-invasive methods to evaluate these alterations with less radiographic exposure are forced oscillation technique, ultrasonic pneumography and impulse oscillometry 76,77…”

Section: Chronic Respiratory Failure Aetiologies and Diagnostic Womentioning

confidence: 99%

Management of Chronic Respiratory Failure in Interstitial Lung Diseases: Overview and Clinical Insights

Faverio¹,

Giacomi²,

Bonaiti³

et al. 2019

Int. J. Med. Sci.

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Interstitial lung diseases (ILDs) may be complicated by chronic respiratory failure (CRF), especially in the advanced stages. Aim of this narrative review is to evaluate the current evidence in management of CRF in ILDs. Many physiological mechanisms underlie CRF in ILDs, including lung restriction, ventilation/perfusion mismatch, impaired diffusion capacity and pulmonary vascular damage. Intermittent exertional hypoxemia is often the initial sign of CRF, evolving, as ILD progresses, into continuous hypoxemia. In the majority of the cases, the development of CRF is secondary to the worsening of the underlying disease; however, associated comorbidities may also play a role. When managing CRF in ILDs, the need for pulmonary rehabilitation, the referral to lung transplant centers and palliative care should be assessed and, if necessary, promptly offered. Long-term oxygen therapy is commonly prescribed in case of resting or exertional hypoxemia with the purpose to decrease dyspnea and improve exercise tolerance. High-Flow Nasal Cannula oxygen therapy may be used as an alternative to conventional oxygen therapy for ILD patients with severe hypoxemia requiring both high flows and high oxygen concentrations. Non-Invasive Ventilation may be used in the chronic setting for palliation of end-stage ILD patients, although the evidence to support this application is very limited.

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“…Guerrero Zuniga et al . report on ultrasonic pneumography as a potential biomarker of small airway abnormalities in HP …”

Section: Interstitial Lung Diseasementioning

confidence: 99%

Year in review 2017: Interstitial lung disease, pulmonary vascular disease and sleep

et al. 2018

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Small airway dysfunction in chronic hypersensitivity pneumonitis

Abstract: Patients with chronic HP have SA abnormalities that are partially revealed by the UPG and IOS tests. Lung volumes, but not gas exchange, improved after treatment with azathioprine and prednisone.

Cited by 16 publications

References 33 publications

Clinical Applications of Impulse Oscillometry

Clinical Applications of Impulse Oscillometry

Management of Chronic Respiratory Failure in Interstitial Lung Diseases: Overview and Clinical Insights

Year in review 2017: Interstitial lung disease, pulmonary vascular disease and sleep

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