2017
DOI: 10.1186/s12942-017-0108-6
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Small-area distribution of multiple sclerosis incidence in western France: in search of environmental triggers

Abstract: BackgroundDespite intensive research over several decades, the etiology of multiple sclerosis (MS) remains poorly understood, although environmental factors are supposedly implicated. Our goal was to identify spatial clusters of MS incident cases at the small-area level to provide clues to local environmental risk factors that might cause or trigger the disease.MethodsA population-based and multi-stage study was performed in the French Brittany region to accurately ascertain the clinical onset of disease durin… Show more

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Cited by 2 publications
(1 citation statement)
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“…This table contains all the characteristics retrieved by the reviewers for each included study: country of origin, year of publication, neurodegenerative disease, environmental factor, geographic factor, study design, study limitations, statistical methods, and outcome. A list of excluded studies [ 1 , 7 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , ...…”
Section: Resultsmentioning
confidence: 99%
“…This table contains all the characteristics retrieved by the reviewers for each included study: country of origin, year of publication, neurodegenerative disease, environmental factor, geographic factor, study design, study limitations, statistical methods, and outcome. A list of excluded studies [ 1 , 7 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , ...…”
Section: Resultsmentioning
confidence: 99%