Small intestinal morphology in weaned piglets fed a diet containing spray-dried porcine plasma

Dijk, A.J. van; Niewold, Theodoor; Margry, R.J.C.F.; Hoven, S.G.C Van Den; Nabuurs, M.J.A.; Stockhofe-Zurwieden, Norbert; Beynen, A.C.

doi:10.1053/rvsc.2001.0478

Cited by 25 publications

(29 citation statements)

References 21 publications

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“…The increase in villus height observed in the pigs fed BC was similar to that observed in weaner pigs fed diets containing spray-dried plasma Touchette et al, 1999), although other experiments have shown no effect of dietary plasma on villus height (Jiang et al, 2000;van Dijk et al, 2001b). The effect of other dietary compounds on villus height after weaning has been investigated.…”

Section: Discussionsupporting

confidence: 62%

Dietary Bovine Colostrum Increases Villus Height and Decreases Small Intestine Weight in Early-weaned Pigs

King¹,

Morel²,

Revell³

et al. 2008

Asian Australas. J. Anim. Sci

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:This experiment examined the effect of dietary spray-dried bovine colostrum on intestinal histology and organ weights in early-weaned pigs. In a randomised complete block design, twelve 14-day-old weaner pigs were offered a diet containing either 5% spray-dried bovine colostrum or no colostrum (control). Diets were formulated to contain 14.8 MJ/kg DE, 1.26% available lysine and to meet or exceed requirements for other nutrients. Piglets were offered the diets for a period of 14 days. No effect of diet on growth rate or feed intake was observed (p>0.10). Small intestine weight was reduced by 12% in piglets consuming dietary bovine colostrum (p< 0.05). Villous height and crypt depth were increased and decreased, respectively, in the proximal jejunum, mid jejunum and distal ileum of pigs consuming dietary bovine colostrum (p<0.05). Mid-jejunal lamina propria CD4 + and CD8 + T lymphocyte density was increased by 28 and 37%, respectively, in piglets consuming dietary bovine colostrum (p<0.05). Diet did not affect thickness of tunica muscularis externa or tunica submucosa (p>0.10). Collectively, these results suggest a positive effect of dietary bovine colostrum on intestinal morphology and immune status in early-weaned pigs.

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Section: Discussionsupporting

confidence: 62%

Dietary Bovine Colostrum Increases Villus Height and Decreases Small Intestine Weight in Early-weaned Pigs

King¹,

Morel²,

Revell³

et al. 2008

Asian Australas. J. Anim. Sci

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“…Compared to results from the control treatment, dietary spray-dried bovine colostrum reduced small intestine villus height at the site 25% along the small intestine, but increased it at the 75% site, whereas spray-dried bovine plasma increased villus height in the 25% and 75% sites, and spray-dried porcine plasma had no effect on villus height in any sampled region of the small intestine. Relating these results to those of other studies evaluating these products is somewhat difficult, since some have not measured or reported intestinal morphology in more than one section of the intestine (Gatnau et al, 1995;Touchette et al, 1997) and, of those that have, most have generally not demonstrated any effect of either spraydried plasma on intestinal morphology at any site of the small intestine (Jiang et al, 2000;Touchette et al, 1999b;van Dijk et al, 2001b, Torrallardona et al, 2003, or bovine colostrum (Huguet et al, 2006). However, one study did report an interaction of dietary plasma with small intestine site, such that the ratio of villus height to crypt depth was increased in the jejunum and ileum, but not the duodenum, in pigs offered a diet containing 3.5% spray-dried plasma for 10 days after weaning at 18 days of age (Spencer et al, 1997).…”

Section: Discussionmentioning

confidence: 82%

“…Coffey and Cromwell (1995) proposed that the antimicrobial components of spray-dried plasma may bind luminal antigens, inhibiting interaction of pathogens with the intestinal mucosa and the negative effect of infection on epithelial barrier function. However, the effect of spraydried plasma on intestinal morphology is variable, with some experiments demonstrating positive effects (Gatnau et al, 1995, Spencer et al, 1997Touchette et al, 1997Touchette et al, , 1999a and others no effect (Touchette et al, 1999b;Jiang et al, 2000;van Dijk et al, 2001bvan Dijk et al, , 2002.…”

Section: Introductionmentioning

confidence: 99%

A comparison of the effects of dietary spray-dried bovine colostrum and animal plasma on growth and intestinal histology in weaner pigs

et al. 2008

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“…In contrast to conventional weaning, villus length is rapidly restored. This could be related to the inclusion of spray-dried plasma in the milk replacer since this is known to increase villus height [8, 60–63]. …”

Section: Discussionmentioning

confidence: 99%

Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets

Vergauwen

Degroote

Prims

et al. 2017

J Animal Sci Biotechnol

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BackgroundIn this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing. In total, 42 pairs of LBW and NBW piglets from 16 litters suckled the sow until d19 of age or were artificially reared starting at d3 until d19 of age. Blood and tissue samples that were collected after euthanasia at 0, 3, 5, 8 and 19 d of age. Histology, ELISA, and Ussing chamber analysis were used to study proximal and distal small intestine histo-morphology, proliferation, apoptosis, tight junction protein expression, and permeability. Furthermore, small intestine, liver and systemic redox parameters (GSH, GSSG, GSH-Px and MDA) were investigated using HPLC.ResultsLBW and NBW artificially reared piglets weighed respectively 40 and 33% more than LBW and NBW sow-reared piglets at d19 (P < 0.01). Transferring piglets to a nursery at d3 resulted in villus atrophy, increased intestinal FD-4 and HRP permeability and elevated GSSG/GSH ratio in the distal small intestine at d5 (P < 0.05). GSH concentrations in the proximal small intestine remained stable, while they decreased in the liver (P < 0.05). From d5 until d19, villus width and crypt depth increased, whereas PCNA, caspase-3, occludin and claudin-3 protein expressions were reduced. GSH, GSSG and permeability recovered in artificially reared piglets (P < 0.05).ConclusionThe results suggest that artificial rearing altered the morphology, permeability and redox state without compromising piglet performance. The observed effects were not depending on birth weight.

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Small intestinal morphology in weaned piglets fed a diet containing spray-dried porcine plasma

Cited by 25 publications

References 21 publications

Dietary Bovine Colostrum Increases Villus Height and Decreases Small Intestine Weight in Early-weaned Pigs

Dietary Bovine Colostrum Increases Villus Height and Decreases Small Intestine Weight in Early-weaned Pigs

A comparison of the effects of dietary spray-dried bovine colostrum and animal plasma on growth and intestinal histology in weaner pigs

Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets

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