Small, stable and biocompatible gold nanoparticles capped with a β-cyclodextrin polymer

Martin‐Trasanco, Rudy; Cao, Roberto; Ponce, Hilda Esperanza Esparza; García-Pupo, Laura; Montero-Cabrera, M. E.

doi:10.1039/c5ra19974c

Cited by 10 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Note that, if to the diameter of the AgNPs core determined by TEM (12.7 nm) twice the diameter of the polymer determined by DLS (3.5 nm) is added, the result corresponds to a total diameter of ca. 20 nm for AgNPs@βCDP, a value that agrees with that obtained from the DLS (21 nm) …”

Section: Resultssupporting

confidence: 87%

“…In contrast to βCD, the polymer resulting from the crosslinking with epichlorohydrin (βCDP) is highly soluble in water . The use of βCDP polymer increases the solubility of the guest, the inclusion constant with respect to the βCD alone and facilitates the solid formulation of the resulted inclusion complex .…”

Section: Introductionmentioning

confidence: 99%

“…Recently, we have used the βCDP polymer to prepare in‐situ small, stable and biocompatible gold nanoparticles through the Turkevich‐Frens methodology. The prepared gold nanoparticles were precipitated and redispersed in water without altering their initial properties …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

From Concentrated Dispersion to Solid β‐Cyclodextrin Polymer‐Capped Silver Nanoparticle Formulation: A Trojan Horse Against Escherichia coli

et al. 2019

View full text Add to dashboard Cite

Preparation of concentrated silver nanoparticles in water remains a challenge today. The intrinsic reactivity of silver, as well as the high surface energy of nanoparticles, make it difficult to handle them without altering their pristine properties. Herein, we report the preparation of concentrated silver nanoparticles (AgNPs) dispersion (2 mM; 1.5⋅10 15 NPs/mL) by reducing Ag + in-situ of a β-cyclodextrin-epichlorohydrin polymer (βCDP) as a capping agent. The prepared nanoparticles (AgNPs@βCDP) with a Surface Plasmon Resonance band at 396 nm, and a hydrodynamic diameter of 21.4 � 1.8 nm, retained both features after being precipitated and redispersed in water. The AgNPs core had a spherical morphology, with a 12.7 � 1.5 nm diameter in size, as determined by TEM. The AgNPs@βCDP showed outstanding bactericidal properties against Escherichia coli (MIC = 0.37 nM), one of the lowest ever achieved for silver nanoparticles. We suggest that the polymer acts as a Trojan horse with AgNPs as payload.

show abstract

Section: Resultssupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

From Concentrated Dispersion to Solid β‐Cyclodextrin Polymer‐Capped Silver Nanoparticle Formulation: A Trojan Horse Against Escherichia coli

et al. 2019

View full text Add to dashboard Cite

show abstract

“…This feature allows CDs to act as phase transfer agents. On the other hand, CD can act as a capping agent for Ag NPs [45,46]. Next, it was elucidated whether this protocol could be generalized to other aldehydes.…”

Section: Study Of the Catalytic Performancementioning

confidence: 99%

Ag Nanoparticles Stabilized on Cyclodextrin Polymer Decorated with Multi-Nitrogen Atom Containing Polymer: An Efficient Catalyst for the Synthesis of Xanthenes

et al. 2020

View full text Add to dashboard Cite

In attempt to broaden the use of cyclodextrin polymer for catalytic purposes, a novel covalent hybrid system was prepared through growth of multi-nitrogen atom containing polymer (PMelamine) derived from reaction of ethylenediamine and 2,4,6-trichloro-1,3,5-triazine on the functionalized cyclodextrin polymer (CDNS). The resulting hybrid system was then utilized as a catalyst support for the immobilization of silver nanoparticles through using Cuscuta epithymum extract as a naturally-derived reducing agent. The catalytic activity of the catalyst, Ag@CDNS-N/PMelamine, for the synthesis of xanthenes through reaction of aldehydes and dimedone in aqueous media was examined. The results showed high catalytic activity and recyclability of the catalyst. It was believed that cyclodextrin in the backbone of the catalyst could act both as a capping agent for Ag nanoparticles and phase transfer agent to bring the hydrophobic substrates in the vicinity of the catalytic active sites and accelerate the reaction rate. Multi-nitrogen atoms on the polymer, on the other hand, could improve the Ag NPs anchoring and suppress their leaching.

show abstract

“…However, it has the drawback of scarce water solubility (1.85 g/100 mL, at 25 °C) [ 20 ]. The low solubility of βCD can be overcome by its crosslinking with epichlorohydrin (βCDP) in an alkaline medium [ 21 , 22 ]. The resulted polymer not only increases the solubility of the guest, but also increases the inclusion constant with respect to the native βCD [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

In-Situ Preparation of CdTe Quantum Dots Capped with a β-Cyclodextrin-Epichlorohydrin Polymer: Polymer Influence on the Nanocrystal’s Optical Properties

et al. 2018

Self Cite

View full text Add to dashboard Cite

β-Cyclodextrin (βCD), the less water soluble of the cyclodextrins, has been used as a capping agent in the preparation of semiconductor nanocrystals or quantum dots (QDs). Nevertheless, no reports have been found in the use of the highly water-soluble polymer of this, prepared by the crosslinking of the βCD units with epichlorohydrin in basic medium (βCDP). This polymer, besides to overcome the low solubility of the βCD, increases the inclusion constant of the guest; two parameters that deserve its use as capping agent, instead of the native cyclodextrin. In the present manuscript, we afforded the in-situ aqueous preparation of cadmium telluride (CdTe) QDs capped with βCDP. The polymer influence on the photoluminescent properties of the nanocrystals was analyzed. The βCDP controls the nanocrystals growth during the Oswald ripening stage. Consequently, the CdTe capped βCDP QDs showed lower Stokes-shift values, higher photoluminescent efficiency, and narrower size distribution than for nanocrystals obtained in the absence of polymer. Transmission electron microscopy (TEM) micrographs and energy dispersive X-ray spectroscopy (EDS) analysis revealed the composition and crystallinity of the CdTe QDs. This βCDP capped CdTe QDs is a potential scaffold for the supramolecular modification of QDs surface.

show abstract

Small, stable and biocompatible gold nanoparticles capped with a β-cyclodextrin polymer

Abstract: Gold nanoparticles capped with a β-cyclodextrin epichlorohydrin polymer resulted to be smaller than 5 nm, stable in physiological fluid and biocompatible, features that denote their capability as scaffold for future applications in nanomedicine.

Cited by 10 publications

References 24 publications

From Concentrated Dispersion to Solid β‐Cyclodextrin Polymer‐Capped Silver Nanoparticle Formulation: A Trojan Horse Against Escherichia coli

From Concentrated Dispersion to Solid β‐Cyclodextrin Polymer‐Capped Silver Nanoparticle Formulation: A Trojan Horse Against Escherichia coli

Ag Nanoparticles Stabilized on Cyclodextrin Polymer Decorated with Multi-Nitrogen Atom Containing Polymer: An Efficient Catalyst for the Synthesis of Xanthenes

In-Situ Preparation of CdTe Quantum Dots Capped with a β-Cyclodextrin-Epichlorohydrin Polymer: Polymer Influence on the Nanocrystal’s Optical Properties

Contact Info

Product

Resources

About