Smart bandage dyed with sensor probe encapsulated in alginate for wound healing monitoring ضمادة ذکية مصبوغة بصبغة استشعار مغلفة بألجينات الکالسيوم لرصد التئام الجروح

Abstract

Novel in-situ dressing bandage-based disposable probe that changes color upon wound healing was developed. Developing colorimetric technical textile pH-sensor can lead to attractive end-use applications as it represents the potential for inexpensive, fast, flexible pH-sensors. Herein we describe the preparation of tricyanofuran-hydrazone based disperse colorant to act as a color changeable pH-sensor. The pH responsive tricyanofuran-hydrazone was encapsulated as a core material in Ca-alginate microcapsule as a wall-former, which was loaded onto a cotton gauze by padding. This reversible color change depending on pH variations was due to charge delocalization of tricyanofuran-hydrazone anion form generated that led to a quinoid-type molecular switching. This tricyanofuran-hydrazone colorant was employed for use in technical textile materials with a pH sensing capability. The approach adopted in the present study was based on dyeing of cotton gauze using tricyanofuran-hydrazone that can afford numerical results for the pH of the wound fluid. The dyed gauze matrix showed a clear reversible color change upon exposure to acid-base solutions as indicated by color coordinates. Our results indicate an obvious color change shown to the naked eye, from orange to purple, which can be recognized at the surface of the employed fabrics when exposed to basic conditions. The surface morphology of the treated cotton gauze was investigated under scanning electron microscopy, energy-dispersive X-ray, and mapping. The treated cotton gauze was studied by exploring of the airpermeability, stiffness, and colorfastness.