Smart injectable self-setting bioceramics for dental applications

Malik, Qurat ul Ain; Iftikhar, Sundus; Zahid, Saba; Safi, Sher Zaman; Khan, Ather Farooq; Muhammad, Nawshad; Ghafoor, Sarah; Khan, Abdul Samad; Shah, Asma Tufail

doi:10.1016/j.msec.2020.110956

Cited by 20 publications

(6 citation statements)

References 46 publications

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“…Moreover, bioceramics have been incorporated in endodontic materials ( Chiang et al, 2016 ), resin composites ( Khalid et al, 2018 ), dental cements such as GICs ( Fuchs et al, 2015 ), and bone cements ( Wang et al, 2016 ). Bioceramics have been used as injectables ( Malik et al, 2020 ), scaffolds ( Khan et al, 2017 ), carrying growth factors ( Lee et al, 2014 ), and stem cells ( Huang et al, 2016 ) for various dental and craniofacial applications. Similarly, novel innovative bioceramic materials are being engineered with tailored properties for various indications in dental surgery.…”

Section: Discussionmentioning

confidence: 99%

The trends of dental biomaterials research and future directions: A mapping review

Iftikhar

Jahanzeb

Saleem³

et al. 2021

The Saudi Dental Journal

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Objective This literature research aimed to compare, contrast and quantify the innovations in the most commonly used dental biomaterials. Methodology Original research articles based on experimental dental biomaterials published between 2007 and 2019 were retrieved and reviewed. A search of electronic databases, PubMed, Scopus, and Web of Science indexed dental/biomaterials journals, has been conducted. The inclusion criteria in this research were: synthesis of experimental dental materials, whereas commercial dental materials, review articles, and clinical trials (case reports) were excluded. Results It was found that the amount of publications related to dental subgingival implants, computer-aided modeling ceramics, aesthetic restorative materials, adhesives cements, ceramics, bioceramics, endodontic materials, bioactive scaffolds, stem cells, and guided-tissue membranes had increased significantly from 2007. At the same time, the number of publications related to dental cements, silver amalgam, and dental alloys has decreased. For characterization of dental materials it was noted that mechanical properties were tested mostly for restorative materials. On the other hand, biological properties were most assessed for dental subgingival implants and endodontic materials, however, physical properties predominantly for bioceramics. Conclusion It is concluded that to meet clinical demands there was more focus on restorative materials that provided better aesthetics, including resin composites, adhesive resin composites (luting cements), zirconia, and other ceramics. The boost in laboratory and animal research related to bioceramics was attributed to their regenerative potential. This current literature study will help growing researchers to consider and judge the direction to which research might be guided in order to plan prospective research projects.

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Section: Discussionmentioning

confidence: 99%

The trends of dental biomaterials research and future directions: A mapping review

Iftikhar

Jahanzeb

Saleem³

et al. 2021

The Saudi Dental Journal

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“…One of the areas in which bioceramics have a wide range of applications is dentistry [ 210 ]. A new class of glass–ceramics based on Li 2 O-SiO 2 called Li disilicate (LD) was conceived for dentistry due to its aesthetics, chemical durability, high fracture strength, and inertness in the buccal environment [ 211 , 212 ].…”

Section: Lithium-doped Bioceramics In Regenerative Medicinementioning

confidence: 99%

Li-Doped Bioactive Ceramics: Promising Biomaterials for Tissue Engineering and Regenerative Medicine

Farmani

Salmeh

Golkar

et al. 2022

JFB

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Lithium (Li) is a metal with critical therapeutic properties ranging from the treatment of bipolar depression to antibacterial, anticancer, antiviral and pro-regenerative effects. This element can be incorporated into the structure of various biomaterials through the inclusion of Li chloride/carbonate into polymeric matrices or being doped in bioceramics. The biocompatibility and multifunctionality of Li-doped bioceramics present many opportunities for biomedical researchers and clinicians. Li-doped bioceramics (capable of immunomodulation) have been used extensively for bone and tooth regeneration, and they have great potential for cartilage/nerve regeneration, osteochondral repair, and wound healing. The synergistic effect of Li in combination with other anticancer drugs as well as the anticancer properties of Li underline the rationale that bioceramics doped with Li may be impactful in cancer treatments. The role of Li in autophagy may explain its impact in regenerative, antiviral, and anticancer research. The combination of Li-doped bioceramics with polymers can provide new biomaterials with suitable flexibility, especially as bio-ink used in 3D printing for clinical applications of tissue engineering. Such Li-doped biomaterials have significant clinical potential in the foreseeable future.

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“…Thereby, the defect is completely filled, since the injected material can adopt the shape and size of a defect. Various applications of injectable materials have been reported, including those in dentistry [4]. Injectable hydrogels have been reported to be created based on proteins [5], but bone filling materials often also include bone cement consisting of calcium phosphates [6].…”

Section: Introductionmentioning

confidence: 99%

The influence of Ca/Mg ratio on autogelation of hydrogel biomaterials with bioceramic compounds

Abalymov¹,

Lengert²,

Meeren³

et al. 2022

Biomaterials Advances

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Smart injectable self-setting bioceramics for dental applications

Cited by 20 publications

References 46 publications

The trends of dental biomaterials research and future directions: A mapping review

The trends of dental biomaterials research and future directions: A mapping review

Li-Doped Bioactive Ceramics: Promising Biomaterials for Tissue Engineering and Regenerative Medicine

The influence of Ca/Mg ratio on autogelation of hydrogel biomaterials with bioceramic compounds

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