Smartphone-assisted ratiometric fluorescence sensing platform and logical device based on polydopamine nanoparticles and carbonized polymer dots for visual and point-of-care testing of glutathione

Yuan, Xucan; Bai, Fujuan; Ye, Heng; Zhao, Hanqing; Zhao, Longshan; Xiong, Zhili

doi:10.1016/j.aca.2021.339165

Cited by 22 publications

(13 citation statements)

References 57 publications

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“…Although most of these methods have high sensitivity, they have some disadvantages, such as high costs, time-consuming sample pretreatments and sophisticated instrument manipulation. Recently, there has been growing interest in the development of pointof-care device testing (POCT) for its low cost and simple and fast response based on colorimetric and fluorescent measurements for the determination of GSH [23][24][25][26][27]. However, the development of these probes is limited for the lack of selectivity, despite possessing excellent optical performances.…”

Section: Introductionmentioning

confidence: 99%

Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device

et al. 2023

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Here, we propose a microfluidic paper-based analytical device (µPAD) implemented with a near-field communication (NFC) tag as a portable, simple and fast colorimetric method for glutathione (GSH) determination. The proposed method was based on the fact that Ag+ could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized blue TMB. Thus, the presence of GSH could cause the reduction of oxidized TMB, which resulted in a blue color fading. Based on this finding, we developed a method for the colorimetric determination of GSH using a smartphone. A µPAD implemented with the NFC tag allowed the harvesting of energy from a smartphone to activate the LED that allows the capture of a photograph of the µPAD by the smartphone. The integration between electronic interfaces into the hardware of digital image capture served as a means for quantitation. Importantly, this new method shows a low detection limit of 1.0 µM. Therefore, the most important features of this non-enzymatic method are high sensitivity and a simple, fast, portable and low-cost determination of GSH in just 20 min using a colorimetric signal.

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Section: Introductionmentioning

confidence: 99%

Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device

et al. 2023

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“…In recent years, the field has evolved from a single physical or chemical input to a combinatorial and sequential operation, showing great potential and broad promise. Molecular logic gates are gradually replacing traditional semiconductor electronic computers with their significant advantages and are used for heavy metal ion detection, environmental monitoring, food safety detection, pre-disease diagnosis, and biosensor research [ 36 , 37 , 38 ]. MOFs-based fluorescent probes are highly selective and sensitive, allowing the construction of chemical sensors for sensing various analytes by host–guest interactions.…”

Section: Introductionmentioning

confidence: 99%

A Novel Turn-On Fluorescence Probe Based on Cu(II) Functionalized Metal–Organic Frameworks for Visual Detection of Uric Acid

et al. 2022

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As an important biomarker in urine, the level of uric acid is of importance for human health. In this work, a Cu(II) functionalized metal–organic framework (Cu2+@Tb-MOFs) is designed and developed as a novel fluorescence probe for wide-range uric acid detection in human urine. The study shows that this fluorescence platform demonstrated excellent pH-independent stability, high water tolerance, and good thermal stability. Based on the strong interaction between metal ions and uric acid, the designed Cu2+@Tb-MOFs can be employed as efficient turn-on fluorescent probes for the detection of uric acid with wide detection range (0~104 µM) and high sensitivity (LOD = 0.65 µM). This probe also demonstrates an anti-interference property, as other species coexisted, and the possibility for recycling. The sensing mechanisms are further discussed at length. More importantly, we experimentally constructed a molecular logic gate operation based on this fluorescence probe for intelligent detection of uric acid. These results suggest the Cu(II) functionalized metal–organic framework can act as a prominent candidate for personalized monitoring of the concentration of uric acid in the human urine system.

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“…18,19 In comparison with visualization by the naked eye, RGB color analysis with a smartphone can offer more excellent accuracy because the naked eye is insensitive to slight color changes. 20 Therefore, developing a portable, visual, accurate and convenient detection tool for Hg 2+ is urgently needed in further research.…”

Section: Introductionmentioning

confidence: 99%

An α-naphtholphthalein-derived colorimetric fluorescent chemoprobe for the portable and visualized monitoring of Hg²⁺by the hydrolysis mechanism

et al. 2022

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Smartphone-assisted ratiometric fluorescence sensing platform and logical device based on polydopamine nanoparticles and carbonized polymer dots for visual and point-of-care testing of glutathione

Cited by 22 publications

References 57 publications

Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device

Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device

A Novel Turn-On Fluorescence Probe Based on Cu(II) Functionalized Metal–Organic Frameworks for Visual Detection of Uric Acid

An α-naphtholphthalein-derived colorimetric fluorescent chemoprobe for the portable and visualized monitoring of Hg²⁺by the hydrolysis mechanism

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Smartphone-assisted ratiometric fluorescence sensing platform and logical device based on polydopamine nanoparticles and carbonized polymer dots for visual and point-of-care testing of glutathione

Cited by 22 publications

References 57 publications

Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device

Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device

A Novel Turn-On Fluorescence Probe Based on Cu(II) Functionalized Metal–Organic Frameworks for Visual Detection of Uric Acid

An α-naphtholphthalein-derived colorimetric fluorescent chemoprobe for the portable and visualized monitoring of Hg2+by the hydrolysis mechanism

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Product

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An α-naphtholphthalein-derived colorimetric fluorescent chemoprobe for the portable and visualized monitoring of Hg²⁺by the hydrolysis mechanism