Smartphone-Based Hand-Held Optical Fiber Fluorescence Sensor for On-Site pH Detection

Liu, Ting; Wang, Wenqi; Ding, He; Yi, Dingrong

doi:10.1109/jsen.2019.2926153

Cited by 31 publications

(11 citation statements)

References 38 publications

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“…24 In 2019, Ting Liu designed an optical fiber pH sensor based on a smartphone platform using a cone-shaped optical fiber combination probe modified by CdSe/ZnS QDs to realize remote and on-site pH detection. 25 In practical applications, sensors that only rely on the fluorescence intensity of QDs are easily affected by the fluctuation of the excitation source, fading of the indicator light, and drift of the detector. To overcome these shortcomings, researchers have designed and developed a ratiometric fluorescence sensor based on reference technology.…”

Section: Introductionmentioning

confidence: 99%

“…In 2014, Pankaj first studied the pH sensing phenomenon of a core–shell CdSe/ZnS QD sensor in the electrolyte–insulator–semiconductor structure . In 2019, Ting Liu designed an optical fiber pH sensor based on a smartphone platform using a cone-shaped optical fiber combination probe modified by CdSe/ZnS QDs to realize remote and on-site pH detection …”

Section: Introductionmentioning

confidence: 99%

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Oxazine-Functionalized CdSe/ZnS Quantum Dots for Photochemical pH Sensing

Zhang

Jin

Song

et al. 2020

ACS Appl. Nano Mater.

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pH is the most important chemical parameter of an aqueous solution, and it is widely used in biochemistry, environmental science, and other fields. In this article, we have successfully prepared an application-type ratiometric photochemical pH sensor combining semiconductor nanomaterial CdSe/ZnS quantum dots (QDs) and oxazine 170 perchlorate (O170). This sensor facilitated fluorescence resonance energy transfer (FRET) between CdSe/ZnS QDs (donor) and O170 (acceptor) due to the dipole–dipole interaction. Molar absorption coefficient, Foster radius, and FRET efficiency were determined, and the experimental FRET efficiency was found to be very close to the theoretical value. Thus, we utilized the interaction of QD nanomaterials and the O170 dye to promote oxazine-functionalized CdSe/ZnS QDs and revealed the principle of the FRET-based sensor. We mixed these two substances to form a sensitive film that covered the end face of an optical fiber. The experimental results showed that the FRET-based fiber-optic pH sensor exhibited a large detection range and good performance in terms of linearity, sensitivity, and repeatability. The pH sensor studied by the photochemical method has great application potential in the fields of marine monitoring and environmental protection.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Oxazine-Functionalized CdSe/ZnS Quantum Dots for Photochemical pH Sensing

Zhang

Jin

Song

et al. 2020

ACS Appl. Nano Mater.

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“…While the previous architectures makes use of both the light source and detector of the phone, other systems proposed in [ 107 , 108 , 109 , 110 , 111 ] maintain a fiber-optic probe but use a different light source. In these cases, the system is still fiber-coupled and compatible with a smartphone, but significant external hardware is required.…”

Section: Smartphone Fiber Optic Sensorsmentioning

confidence: 99%

“…Here, the proposed application is the detection of mercury cations (Hg 2+ ) in the 1–1000 nM range. A similar system was described in [ 110 ] for pH detection and in [ 111 ] for dual-channel fluorescence monitoring.…”

Section: Smartphone Fiber Optic Sensorsmentioning

confidence: 99%

Cost-Effective Fiber Optic Solutions for Biosensing

et al. 2022

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In the last years, optical fiber sensors have proven to be a reliable and versatile biosensing tool. Optical fiber biosensors (OFBs) are analytical devices that use optical fibers as transducers, with the advantages of being easily coated and biofunctionalized, allowing the monitorization of all functionalization and detection in real-time, as well as being small in size and geometrically flexible, thus allowing device miniaturization and portability for point-of-care (POC) testing. Knowing the potential of such biosensing tools, this paper reviews the reported OFBs which are, at the moment, the most cost-effective. Different fiber configurations are highlighted, namely, end-face reflected, unclad, D- and U-shaped, tips, ball resonators, tapered, light-diffusing, and specialty fibers. Packaging techniques to enhance OFBs’ application in the medical field, namely for implementing in subcutaneous, percutaneous, and endoscopic operations as well as in wearable structures, are presented and discussed. Interrogation approaches of OFBs using smartphones’ hardware are a great way to obtain cost-effective sensing approaches. In this review paper, different architectures of such interrogation methods and their respective applications are presented. Finally, the application of OFBs in monitoring three crucial fields of human life and wellbeing are reported: detection of cancer biomarkers, detection of cardiovascular biomarkers, and environmental monitoring.

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“…Recent advancements in microcontrollers and microprocessors have ushered in a new wave of low-cost equipment for environmental sensing [ 7 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 ]. For example, commercial in situ chlorophyll a fluorometers cost more than USD 3000 while low-cost alternatives with comparable performance can be produced for less than 5% of that cost [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Hardware Selection and Performance of Low-Cost Fluorometers

Hixson

Ward

2022

Sensors

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Access to and extensive use of fluorometric analyses is limited, despite its extensive utility in environmental transport and fate. Wide-spread application of fluorescent tracers has been limited by the prohibitive costs of research-grade equipment and logistical constraints of sampling, due to the need for high spatial resolutions and access to remote locations over long timescales. Recently, low-cost alternatives to research-grade equipment have been found to produce comparable data at a small fraction of the price for commercial equipment. Here, we prototyped and benchmarked performance of a variety of fluorometer components against commercial units, including performance as a function of tracer concentration, turbidity, and temperature, all of which are known to impact fluorometer performance. While component performance was found to be comparable to the commercial units tested, the best configuration tested obtained a functional resolution of 0.1 ppb, a working concentration range of 0.1 to >300 ppb, and a cost of USD 59.13.

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Smartphone-Based Hand-Held Optical Fiber Fluorescence Sensor for On-Site pH Detection

Cited by 31 publications

References 38 publications

Oxazine-Functionalized CdSe/ZnS Quantum Dots for Photochemical pH Sensing

Oxazine-Functionalized CdSe/ZnS Quantum Dots for Photochemical pH Sensing

Cost-Effective Fiber Optic Solutions for Biosensing

Hardware Selection and Performance of Low-Cost Fluorometers

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