Smartphone-integrated tri-color fluorescence sensing platform based on acid-sensitive fluorescence imprinted polymers for dual-mode visual intelligent detection of ibuprofen, chloramphenicol and florfenicol

Tang, Kangling; Chen, Yu; Wang, Xiangni; Zhou, Qin; Lei, Huibin; Yang, Zhaoxia; Zhang, Zhaohui

doi:10.1016/j.aca.2023.341174

Cited by 24 publications

(2 citation statements)

References 53 publications

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“…Ibuprofen is classified as a nonsteroidal anti-inflammatory drug (NSAID), whereas chloramphenicol and florfenicol belong to the antibiotic class of medications. Tang's team [40] has developed a novel sensing platform using acid-sensitive fluorescence-imprinted polymers integrated with a smartphone for detecting ibuprofen, chloramphenicol, and florfenicol. The fluorescence-imprinted polymers, including Fe/Zr-MOF@MIP, g-CdTe@ZIF-67@MIP, and r-CdTe@ZIF-67@MIP, are synthesized through sol-gel polymerization.…”

Section: Applications Of Bio-chemical Optical Sensors Using a Smartphonementioning

confidence: 99%

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Smartphone-Based Portable Bio-Chemical Sensors: Exploring Recent Advancements

Bui,

Thangavel,

Sharipov

et al. 2023

Chemosensors

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Traditionally, analytical chemistry and diagnosis relied on wet laboratories and skilled professionals utilizing sophisticated instruments for sample handling and analysis. However, with the development of novel materials and sensing techniques, there has been a significant shift towards the use of standalone sensors, allowing tests to be conducted on-site or even in real time, leading to cost- and time-efficiency. With their widespread adoption globally, smartphones have emerged as an ideal platform for such sensors, boasting extensive sensor capabilities, advanced processing power, and communication functionalities. Smartphone-based assays make use of optical and electrochemical sensors, utilizing built-in cameras, ambient light sensors, and other features for optical sensing, while the micro-USB port, Bluetooth, and wireless connection facilitate data transmission and analog voltage application for electrochemical sensing. Previous overview papers have explored smartphone-based sensing in specific domains; this review provides a comprehensive examination of recent advancements in smartphone-based sensors, encompassing both optical and electrochemical sensing methods. The review provides the fundamental principles of these sensors and their implementation using smartphones, showcases recent applications, and presents innovative designs that take advantage of the inherent functionalities and sensor capabilities of smartphones. The review concludes by offering an outlook on the prospects of smartphone-based sensing and includes a reflective section emphasizing the potential impact of sensors in chemical and biological analyses. This comprehensive resource aims to provide information to researchers and practitioners interested in using smartphones for cutting-edge analytical methodologies.

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Section: Applications Of Bio-chemical Optical Sensors Using a Smartphonementioning

confidence: 99%

“…10 pM, 8.5 pM, and 5.5 nM [40] Protease biomarker Smartphone-based colorimetric paper strip test. 5.7 pM [41] Water in organic solvent Smartphone adapter for fluorescence imaging.…”

Section: Ambient Light Sensor Of Smartphone-based Biosensorsmentioning

confidence: 99%

Smartphone-Based Portable Bio-Chemical Sensors: Exploring Recent Advancements

Bui,

Thangavel,

Sharipov

et al. 2023

Chemosensors

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Introducing molecular imprinting onto nanozymes: toward selective catalytic analysis

Bu,

Huang,

et al. 2024

Anal Bioanal Chem

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Signal amplification in molecular sensing by imprinted polymers

Chen,

Li,

Xue

et al. 2024

Microchim Acta

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In the field of sensing, the development of sensors with high sensitivity, accuracy, selectivity, sustainability, simplicity, and low cost remains a key focus. Over the past decades, optical and electrochemical sensors based on molecular imprinting techniques have garnered significant attention due to the above advantages. Molecular imprinting technology utilizes molecularly imprinted polymers (MIPs) to mimic the specific recognition capabilities of enzymes or antibodies for target molecules. Recently, MIP-based sensors rooting in signal amplification techniques have been employed to enhance molecular detection level and the quantitative ability for environmental pollutants, biomolecules, therapeutic compounds, bacteria, and viruses. The signal amplification techniques involved in MIP-based sensors mainly cover nucleic acid chain amplification, enzyme-catalyzed cascade, introduction of high-performance nanomaterials, and rapid chemical reactions. The amplified analytical signals are centered around electrochemical, fluorescence, colorimetric, and surface-enhanced Raman techniques, which can effectively realize the determination of some low-abundance targets in biological samples. This review highlights the recent advancements of electrochemical/optical sensors based on molecular imprinting integrated with various signal amplification strategies and their dedication to the study of trace biomolecules. Finally, future research directions on developing multidimensional output signals of MIP-based sensors and introducing multiple signal amplification strategies are proposed. Graphical abstract

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Smartphone-integrated tri-color fluorescence sensing platform based on acid-sensitive fluorescence imprinted polymers for dual-mode visual intelligent detection of ibuprofen, chloramphenicol and florfenicol

Cited by 24 publications

References 53 publications

Smartphone-Based Portable Bio-Chemical Sensors: Exploring Recent Advancements

Smartphone-Based Portable Bio-Chemical Sensors: Exploring Recent Advancements

Introducing molecular imprinting onto nanozymes: toward selective catalytic analysis

Signal amplification in molecular sensing by imprinted polymers

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