Smoking cessation improves olfactory functions

Dinç, Ayşe Seçil Kayalı; Şengezer, Tijen; Çayönü, Melih; Şahin, Müslüm

doi:10.1002/lary.27992

Cited by 18 publications

(18 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Prior studies have found both negative and positive effects of smoking on olfactory function in the general population. 13,14 Although smoking cessation seems to improve both subjective and measured olfactory function, 15,16 the underlying pathogenesis linking olfactory dysfunction and smoking is not clear, and several possible explanations exist. Tobacco smoke exposure may cause increased apoptosis in olfactory neurons, which can overwhelm the regenerative capacity.…”

Section: Introductionmentioning

confidence: 99%

The Association Between Smoking on Olfactory Dysfunction in 3,900 Patients With Olfactory Loss

Fjældstad

Ovesen

Hummel³

2020

The Laryngoscope

View full text Add to dashboard Cite

Objectives/Hypothesis The association between smoking and olfactory loss remains a conundrum. Prior studies have found negative and positive effects of smoking on olfactory function in the general population. However, smoking cessation seems to improve both rated and measured olfactory function. The purpose of this study was to investigate the olfactory function and smoking habits in patients with olfactory loss caused by different etiologies to unveil underlying patterns related to smoking. Study Design Retrospective observational study. Methods Patients were included from two specialized taste and smell centers. Patients underwent olfactory testing, clinical examination including rhinoscopy, and the underlying etiology was identified. Patterns of olfactory test scores, demographics, and etiologies were analyzed. Results In total, 3,900 patients with olfactory loss were included. Of these, 521 were current smokers, and 316 were former smokers. Patients with a history of smoking did not have significantly lower olfactory function. Current smokers were more often affected by posttraumatic olfactory loss, but not sinonasal, postviral, or idiopathic olfactory loss. Conclusions Current smoking, but not former smoking, was associated with posttraumatic olfactory loss. In relation to measured olfactory function, a history of smoking was not associated to lower olfactory scores. Our findings suggest that the general recommendations of smoking cessation for patients with olfactory loss are especially relevant for patients with posttraumatic olfactory loss. The nature of this association between current smoking and posttraumatic olfactory loss has yet to be elucidated. Level of Evidence 2b Laryngoscope, 131:E8–E13, 2021

show abstract

Section: Introductionmentioning

confidence: 99%

The Association Between Smoking on Olfactory Dysfunction in 3,900 Patients With Olfactory Loss

Fjældstad

Ovesen

Hummel³

2020

The Laryngoscope

View full text Add to dashboard Cite

show abstract

“…They hypothesized that insufficient regeneration of olfactory epithelium was responsible for the lack of improvement in the odor threshold score. 9 Tobacco smoke has been proven to be harmful to cognitive function in studies. 30,31 It has been established before that there is a connection between olfactory and cognitive function.…”

Section: Discussionmentioning

confidence: 99%

“…They hypothesized that insufficient regeneration of olfactory epithelium was responsible for the lack of improvement in the odor threshold score. 9 …”

Section: Discussionmentioning

confidence: 99%

“…5,7 Previous reports indicated that smoking is one of the major causes of olfactory dysfunction. [8][9][10] However, the consequences of passive smoking on olfactory function were much less well investigated.…”

Section: Introductionmentioning

confidence: 99%

“… 5 , 7 Previous reports indicated that smoking is one of the major causes of olfactory dysfunction. 8 , 9 , 10 However, the consequences of passive smoking on olfactory function were much less well investigated. No studies have analyzed the factors associated with objective olfactory test results in a regression model in passive smokers.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Olfactory dysfunction in passive vs active smoking

Kurnaz

Tahir

Kavaz

2021

Laryngoscope Investig Oto

View full text Add to dashboard Cite

Background: The aim of this study is to assess the olfactory functions of passive smokers compared to active smokers and nonsmokers.Methods: This prospective case-control study included 30 nonsmokers, 30 passive smokers, and 30 active smoker participants. All groups were matched for gender and age. The Sino-Nasal Outcome Test 22 (SNOT-22) and Sniffin' Sticks test battery were administered to all subjects. Threshold (T), discrimination (D), and identification (I) scores were noted. Olfactory function was subjectively assessed as 0: severe dysfunction and 5: no problem.Results: Overall, TDI scores of active smokers (24.78 ± 3.02) and passive smokers (24.90 ± 2.45) were significantly lower than nonsmokers (34.23 ± 3.46). There was no statistically significant difference between passive smokers and smokers (F (2,87) = 13.47, P < .001)). All subscores are negatively affected by active or passive smoking. The greatest impact of smoking was on threshold scores (η 2 T = 0.719), followed by identification (η 2 I = 0.353) and discrimination (η 2 D = 0.282) scores. SNOT-22 and TDI scores were weakly (r = À.352) correlated as subjective assessment, and TDI scores were moderately correlated (r: .539) (P values < .001). Age and pack-years cigarette dosage had a negative effect on the TDI score (TDI = 26.386 À (0.084 Â age) À (0.072 Â Pack.Year)) according to stepwise linear regression model (F = 10.187; P = .001).Conclusions: Passive smoking has nearly the same adverse effect on olfactory function as active smoking. The threshold scores are the most negatively affected. The olfactory effect of cigarette smoke may not be directly related to nasal inflammation.Olfactory neuronal pathways should be investigated to elucidate the exact pathophysiology.

show abstract

International consensus statement on allergy and rhinology: Olfaction

Patel

Holbrook

Turner

et al. 2022

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

Background:The literature regarding clinical olfaction, olfactory loss, and olfactory dysfunction has expanded rapidly over the past two decades, with an exponential rise in the past year. There is substantial variability in the quality of this literature and a need to consolidate and critically review the evidence. It is with that aim that we have gathered experts from around the world to produce this International Consensus on Allergy and Rhinology: Olfaction (ICAR:O). Methods: Using previously described methodology, specific topics were developed relating to olfaction. Each topic was assigned a literature review, evidence-based review, or evidence-based review with recommendations format as dictated by available evidence and scope within the ICAR:O document. Following iterative reviews of each topic, the ICAR:O document was integrated and reviewed by all authors for final consensus. Results:The ICAR:O document reviews nearly 100 separate topics within the realm of olfaction, including diagnosis, epidemiology, disease burden, diagnosis, testing, etiology, treatment, and associated pathologies. Conclusion:This critical review of the existing clinical olfaction literature provides much needed insight and clarity into the evaluation, diagnosis, and treatment of patients with olfactory dysfunction, while also clearly delineating gaps in our knowledge and evidence base that we should investigate further.

show abstract

Smoking cessation improves olfactory functions

Cited by 18 publications

References 20 publications

The Association Between Smoking on Olfactory Dysfunction in 3,900 Patients With Olfactory Loss

The Association Between Smoking on Olfactory Dysfunction in 3,900 Patients With Olfactory Loss

Olfactory dysfunction in passive vs active smoking

International consensus statement on allergy and rhinology: Olfaction

Contact Info

Product

Resources

About