2006
DOI: 10.1055/s-2006-939320
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Smoking upregulates α4ß2* nicotinic acetylcholine receptors in brainstem and cerebellum

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“…Some molecular effects of nicotine could explain why individuals with severe NUD might have acquired a larger thalamus compared to individuals with low severity. Smoking is known to promote the upregulation of nAChR, which are found with largest densities in the thalamus (33). Also, higher levels of nAChR before smoking cessation treatment increases the likelihood of treatment success (34).…”
Section: Discussionmentioning
confidence: 99%
“…Some molecular effects of nicotine could explain why individuals with severe NUD might have acquired a larger thalamus compared to individuals with low severity. Smoking is known to promote the upregulation of nAChR, which are found with largest densities in the thalamus (33). Also, higher levels of nAChR before smoking cessation treatment increases the likelihood of treatment success (34).…”
Section: Discussionmentioning
confidence: 99%