Smoothing the mosaic subclinical melanoderma by calcipotriol

Piérard‐Franchimont, C.; Paquet, Philippe; Quatresooz, Pascale; Ge, Piérard

doi:10.1111/j.1468-3083.2006.02048.x

Cited by 23 publications

(16 citation statements)

References 25 publications

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“…For example, epidemiological evidence suggests that sunlight deprivation with associated reduction in the circulating levels of vitamin D 3 may result in increased incidence of carcinomas of the breast, colon and prostate [9]. Vitamin D 3 and its analogues also modulate the biology of keratinocytes and melanocytes of the skin in vivo [10].…”

Section: Regulation Of the Cutaneous Neuroendocrine Systemmentioning

confidence: 99%

Skin in maturity: the endocrine and neuroendocrine pathways

Quatresooz

Piérard‐Franchimont

Kharfi

et al. 2007

Intern J of Cosmetic Sci

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SynopsisIrrespective of age, most of the skin components are under the physiological control of endocrine and neuroendocrine factors. There is evidence that skin ageing appears complex showing much interindividual variability. Conceptually, ageing is a single biological process that is influenced and modulated by a series of various internal and exogenous factors. Among them, hormones and neuroendocrine signals play key roles in several ways. Ageing of most endocrine glands will in turn alter the skin biology. In addition, the age-related reduction in the intrinsic neuroendocrine activity of the skin will also alter the ageing rate of this organ. At last, various endocrinopathies will boost or conversely decrease the severity of the signs of cutaneous ageing. Ré suméIndépendamment de l'âge, la plupart des composants de la peau sont sous le contrôle physiologique de facteurs endocriniens et neuroendocriniens. Il semble évident, que le vieillissement cutané apparaît complexe, révélant une grande variabilité interindividuelle. Conceptuellement, le vieillissement est un processus biologique unique qui est influencé et modulé par une ensemble de divers facteurs internes et externes. Parmi eux, les hormones et les signaux neuroendocriniens jouent des rôles clés de diverses manières. D'une part, le vieillissement de la plupart des glandes endocrines va, par voie de conséquence, altérer la biologie cutanée. D'autre part, la réduction liée à l'âge de l'activité neuroendocrinienne intrinsèque de la peau altère aussi la progression du vieillissement de cet organe. Enfin, diverses endocrinopathies peuvent accélérer ou, en revanche, réduire la sévérité des signes du vieillissement cutané.

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Section: Regulation Of the Cutaneous Neuroendocrine Systemmentioning

confidence: 99%

Skin in maturity: the endocrine and neuroendocrine pathways

Quatresooz

Piérard‐Franchimont

Kharfi

et al. 2007

Intern J of Cosmetic Sci

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“…Beyond conventional cosmetic whitening agents, some drugs alter the activity of the epidermal melanin units. Both topical corticosteroids and vitamin D analogues decrease the MSM severity as assessed by the ULEV method [ 16 ].…”

Section: Assessment Of Whitening Agentsmentioning

confidence: 99%

Visioscan-Driven ULEV Method

Pierard

Piérard-Franchimont

Pierard

2013

Non Invasive Diagnostic Techniques in Clinical Dermatology

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“…They recalled rare sunburns on the scalp. The bald area and the forehead were scrutinized using the previously described ULEV method (17)(18)(19)(20).…”

Section: Methodsmentioning

confidence: 99%

“…UV light photography, in particular the UV light-enhanced visualization (ULEV) method (1,(17)(18)(19)(20), is a convenient means for highlighting early signs of this type of skin weathering.…”

Section: Introductionmentioning

confidence: 99%

Epidermal field carcinogenesis in bald-headed: An attempt at finetuning early non-invasive detection

et al. 2009

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Abstract. Skin weathering and photoaging of the balding scalp have not attracted much investigative attention so far. However, the concept of field cancerization, in particular actinic field carcinogenesis, is likely applicable to this part of the body. The aim of the study was to finetune the epidermal actinic changes present on hairlessness scalp. The ultraviolet light-enhanced visualization (ULEV) method was used to assess a series of 50 healthy men older than 50 years with documented baldness for over 15 years. They were scrutenized looking for altered epidermal structures corresponding to photoaging-associated changes. Attention was focused on the faint mosaic melanoderma (FMM) and atypical scaliness. Observations were made on the scalp and forehead. FMM was recognized in each case. It presented either as a single manifestation of photoaging or it was associated with an unusual pattern of discrete rimmed scaliness. In this latter case histology and morphometry disclosed keratinocyte dysplasia. A similar scaly pattern was not seen on the forehead. Subtle skin surface changes were disclosed on long-standing sun-exposed balding scalps. The scaly aspect was distinct from dandruff, seborrheic dermatitis or any other common inflammatory scalp dermatosis. The presently described changes had not previously been described during early balding. It is suggested that the presently described condition may be associated with or indicative for actinic field carcinogenesis and incipient keratinocyte dysplasia.

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Smoothing the mosaic subclinical melanoderma by calcipotriol

Abstract: The decreased heterogeneity in MSM after calcipotriol applications suggests a control of the epidermal melanocyte unit by the vitamin D(3) derivative.

Cited by 23 publications

References 25 publications

Skin in maturity: the endocrine and neuroendocrine pathways

Skin in maturity: the endocrine and neuroendocrine pathways

Visioscan-Driven ULEV Method

Epidermal field carcinogenesis in bald-headed: An attempt at finetuning early non-invasive detection

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