Sneddon’s syndrome in a child

Gottlöber, Petra; Bezold, Guntram; Schaer, A.; Stolz, Wilhelm; Friesecke, Iris; Peter, R; Kerscher, M.

doi:10.1046/j.1365-2133.2000.03315.x

Cited by 11 publications

(3 citation statements)

References 8 publications

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“…This syndrome commonly affects middle-aged (20± 40 years) women and is very rare in children or young adults [16]. As far as we know, only 3 patients younger than 18 years have been described [17,18]. The clinical spectrum of SS is similar to that seen in PAPS.…”

Section: Discussionmentioning

confidence: 87%

RECURRENT ARTERIAL THROMBOSIS IN A CHILD: Primary Antiphospholipid Antibody Syndrome

Uysal

Doğu²,

Kürekçi³

et al. 2002

Pediatric Hematology and Oncology

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Antiphospholipid antibody syndrome (APS) is characterized by the association of recurrent arterial or venous thrombosis or recurrent fetal wastage and the presence of circulating antiphospholipid antibodies, detected as anticardiolipin antibodies or lupus anticoagulant. The authors report an 8-year-old girl, who presented with central retinal artery occlusion and live do reticularis and was diagnosed as APS. Despite the proper anticoagulant treatment she had several cerebral ischemic events and died 29 months after the diagnosis. A larger number of pediatric case investigations will be required for better understanding and treating this rare thrombotic disorder.

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Section: Discussionmentioning

confidence: 87%

RECURRENT ARTERIAL THROMBOSIS IN A CHILD: Primary Antiphospholipid Antibody Syndrome

Uysal

Doğu²,

Kürekçi³

et al. 2002

Pediatric Hematology and Oncology

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“…We identified 97 case series and reports with 426 individuals with Sneddon's syndrome. In 42 case reports and 23 case series, containing a total of 208 individuals, the presence or absence of headache is not mentioned (15–64). The female to male ratio for this group is 3 : 1.…”

Section: Resultsmentioning

confidence: 99%

Sneddon's Syndrome

et al. 2006

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Sneddon's syndrome refers to the enigmatic association of ischaemic stroke and livedo reticularis. We review the Sneddon's syndrome literature examining the association of this condition with headache, including migraine. Case reports and series are stratified into two groups based on headache reference. In the group without a reference to headache, there are 208 persons, with a female to male ratio of 3 : 1. In the headache reference group, there are 175 persons, with a female to male ratio of 3.5 : 1. The proportion with headache in this second group is 58% (102 individuals), with headache described as migraine in 28 (27.5%) of the headache subjects, including six with migraine with aura. The frequency of headache is not significantly higher in persons with positive anti-phospholipid antibodies compared with the negative cohort (43% vs. 32%, P = 0.07). A review of the histopathological, radiological and serological data in Sneddon's syndrome and migraine underscores the plausibility of an association. Considered in the context of increased risk of stroke with migraine, a higher frequency of livedo in migraineurs with stroke, and the association of migraine and livedo reticularis, the question of whether livedo reticularis may be a risk marker for stroke in migraineurs is an area for further study.

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“…Lebensjahrzehnt) auf. Frauen sind etwa doppelt so häufig wie Männer betroffen [48]. Die Erkrankung beginnt mit einer generalisierten Livedo racemosa, mit den Prädilektionsstellen Beine, Oberarme, Gesäß und Rücken.…”

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Diagnostik und histologische Besonderheiten von Systemvaskulitiden – Teil 2

et al. 2016

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Zusammenfassung Unter dem Begriff der Systemvaskulitiden werden diejenigen Entz?ndungen zusammengefasst, die zum einen neben der Hautbeteiligung auch eine Vielfalt an Organbeteiligungen aufweisen k?nnen, welche durch einen m?glicherweise lebensbedrohlichen Verlauf gekennzeichnet sind, als auch die Entz?ndungen an den gro?en Gef??en (Aorta, Organgef??en). Sui generis ergeben sich hierdurch andere Anforderungen an die Diagnostik, die Therapie und das Therapiemonitoring dieser Patienten und die Notwendigkeit eines engen interdisziplin?ren Managements dieser Erkrankungen zwischen den beteiligten Fachrichtungen, insbesondere Dermatologie und Rheumatologie. Die Rolle des Dermatologen ist in Bezug auf diese Vaskulitiden die des ?Weichenstellers? und er ist f?r die Unterscheidung der rein kutanen Vaskulitiden von Vaskulitiden mit potenziell lebensbedrohlichem Verlauf durch Multiorganbeteiligung verantwortlich. Daher werden in Teil 2 dieser Weiterbildungsreihe die dermatologisch relevanten Charakteristika der sog. Systemvaskulitiden schwerpunktm??ig dargestellt, aktuelle Begriffe und Namens?nderungen diskutiert und histologische Befunde pr?sentiert.

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Sneddon’s syndrome in a child

Cited by 11 publications

References 8 publications

RECURRENT ARTERIAL THROMBOSIS IN A CHILD: Primary Antiphospholipid Antibody Syndrome

RECURRENT ARTERIAL THROMBOSIS IN A CHILD: Primary Antiphospholipid Antibody Syndrome

Sneddon's Syndrome

Diagnostik und histologische Besonderheiten von Systemvaskulitiden – Teil 2

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