Social Peptides: Measuring Urinary Oxytocin and Vasopressin in a Home Field Study of Older Adults at Risk for Dehydration

Reyes, Teófilo L.; Galinsky, Adena M.; Hoffmann, Joscelyn N.; You, Hannah; Ziegler, Toni E.; McClintock, Martha K.

doi:10.1093/geronb/gbu104

Cited by 31 publications

(19 citation statements)

References 26 publications

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“…Furthermore, urinary OT levels represent an average measure during the time required to fill the bladder and void, as opposed to the instantaneous measure of plasma OT levels. Researchers have claimed that the acidity of the urine acts as a preserving agent and prevents OT from degrading prior to assay (Reyes et al, 2014). In order to minimize stressful procedures, we did not catheterize infants for a more instantaneous measure.…”

Section: Discussionmentioning

confidence: 99%

Plasma and Urinary Oxytocin Trajectories in Extremely Premature Infants During NICU Hospitalization

Weber

Harrison

Sinnott

et al. 2017

Biological Research For Nursing

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Extremely premature infants are at great risk for poor neurodevelopmental outcomes, in part because neurologic structures designed to mature in the womb must now do so in the extrauterine environment. Reliable biomarkers of neurodevelopment are especially critical in this population, as behavioral measures can be unreliable due to immaturity of the premature infant nervous system. Oxytocin (OT) has the potential to be a marker of neurobiological processes that offer infant neuroprotection. However, no studies have measured OT in the plasma and urine of premature infants. The purposes of this study were to describe plasma and urine OT levels of premature infants through 34 weeks corrected gestational age (CGA), determine whether plasma and urine OT are correlated, and explore associations between infant demographics and OT trajectories. Plasma and urine from 37 premature infants, born at gestational ages 25–28 6/7 weeks, were longitudinally collected at 14 days of life, then weekly until 34 weeks CGA. Plasma OT decreased with age, at a rate of 15% per week, and exhibited strong stability within infants. Urine OT was not correlated with plasma OT and did not show a significant trend over time; thus, urine may not be a reliable, noninvasive measurement in this population. Apgar score was the only infant demographic characteristic associated with plasma OT. Given the novelty of this work, replication is needed to confirm these findings, and future research should explore potential mechanisms (e.g., stress, normal maturation, and social experiences) that contribute to declining plasma OT levels in premature infants.

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Section: Discussionmentioning

confidence: 99%

Plasma and Urinary Oxytocin Trajectories in Extremely Premature Infants During NICU Hospitalization

Weber

Harrison

Sinnott

et al. 2017

Biological Research For Nursing

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“…As all samples were stored together, the loss was probably similar, leading to a systematic error and limited impact on the investigated association. Limited data suggest that OT is resistant to freeze-thaw cycle in urines [21]. OT used as a drug was stable for 12 months at 4°C and for 1 month at 25°C [22].…”

Section: Discussionmentioning

confidence: 99%

Oxytocin and bone status in men: analysis of the MINOS cohort

Breuil

Fontas²,

Chapurlat

et al. 2015

Osteoporos Int

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“…In all relevant analyses, the values for T and OT were base‐10 log‐transformed to adjust for non‐normal distribution of the data. Because the low control CV for OT is higher than ideal, we adjusted the OT values for the assay plate on which they run to remove the effect of between‐plate variability (Reyes et al, ). To do so, we regressed the log‐transformed OT values on the plate number, took the residuals of the regression model, and added the mean (of log‐transformed OT) back to the residuals before converting the adjusted OT variable to a z ‐score.…”

Section: Methodsmentioning

confidence: 99%

Mothers' and fathers' joint profiles for testosterone and oxytocin in a small‐scale fishing‐farming community: Variation based on marital conflict and paternal contributions

et al. 2019

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Introduction Testosterone and oxytocin are psychobiological mechanisms that interrelate with relationship quality between parents and the quantity and quality of parenting behaviors, thereby affecting child outcomes. Their joint production based on family dynamics has rarely been tested, particularly cross‐culturally. Methods We explored family function and salivary testosterone and oxytocin in mothers and fathers in a small‐scale, fishing‐farming society in Republic of the Congo. Fathers ranked one another in three domains of family life pertaining to the local cultural model of fatherhood. Results Fathers who were viewed as better providers had relatively lower oxytocin and higher testosterone than men seen as poorer providers, who had lower testosterone and higher oxytocin. Fathers also had higher testosterone and lower oxytocin in marriages with more conflict, while those who had less marital conflict had reduced testosterone and higher oxytocin. In contrast, mothers in conflicted marriages showed the opposite profiles of relatively lower testosterone and higher oxytocin. Mothers had higher oxytocin and lower testosterone if fathers were uninvolved as direct caregivers, while mothers showed an opposing pattern for the two hormones if fathers were seen as involved with direct care. Conclusions These results shed new light on parents' dual oxytocin and testosterone profiles in a small‐scale society setting and highlight the flexibility of human parental psychobiology when fathers' roles and functions within families differ across cultures.

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Social Peptides: Measuring Urinary Oxytocin and Vasopressin in a Home Field Study of Older Adults at Risk for Dehydration

Cited by 31 publications

References 26 publications

Plasma and Urinary Oxytocin Trajectories in Extremely Premature Infants During NICU Hospitalization

Plasma and Urinary Oxytocin Trajectories in Extremely Premature Infants During NICU Hospitalization

Oxytocin and bone status in men: analysis of the MINOS cohort

Mothers' and fathers' joint profiles for testosterone and oxytocin in a small‐scale fishing‐farming community: Variation based on marital conflict and paternal contributions

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