Soft Contact Lenses to Optimize Vision in Adults with Idiopathic Infantile Nystagmus: A Pilot Parallel Randomized Controlled Trial

Theodorou, Maria; Quartilho, Ana; Xing, Wen; Bunce, Catey; Rubin, Gary S.; Adams, Gillian; Dahlmann‐Noor, Annegret

doi:10.1080/09273972.2017.1418394

Cited by 14 publications

(8 citation statements)

References 26 publications

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“…Theodorou et al [ 44 ] reported a pilot randomised control trial comparing fully corrective SCL with plano SCL in a group of 38 adult idiopaths. Despite the small effect size, there was an improvement in best corrected VA (BCVA) in both groups along with an improvement in some of the waveform parameters, in keeping with published data.…”

Section: Treatments and Ongoing Medical Carementioning

confidence: 99%

Management of nystagmus in children: a review of the literature and current practice in UK specialist services

Self

Dunn

Erichsen

et al. 2020

Eye

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Nystagmus is an eye movement disorder characterised by abnormal, involuntary rhythmic oscillations of one or both eyes, initiated by a slow phase. It is not uncommon in the UK and regularly seen in paediatric ophthalmology and adult general/strabismus clinics. In some cases, it occurs in isolation, and in others, it occurs as part of a multisystem disorder, severe visual impairment or neurological disorder. Similarly, in some cases, visual acuity can be normal and in others can be severely degraded. Furthermore, the impact on vision goes well beyond static acuity alone, is rarely measured and may vary on a minute-to-minute, day-to-day or month-to-month basis. For these reasons, management of children with nystagmus in the UK is varied, and patients report hugely different experiences and investigations. In this review, we hope to shine a light on the current management of children with nystagmus across five specialist centres in the UK in order to present, for the first time, a consensus on investigation and clinical management.

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Section: Treatments and Ongoing Medical Carementioning

confidence: 99%

Management of nystagmus in children: a review of the literature and current practice in UK specialist services

Self

Dunn

Erichsen

et al. 2020

Eye

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“…The self-administered VFQ-25 formed part of the baseline clinical data in an unmasked pilot parallel-randomised control trial assessing the use of contact lenses to optimise vision in adults with IINS 25 . All participants were required to complete the VFQ-25 questionnaire at the baseline study visit prior to randomisation.…”

Section: Methodsmentioning

confidence: 99%

Visual functioning in adults with Idiopathic Infantile Nystagmus Syndrome (IINS)

et al. 2018

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“…Some studies report improvements in visual acuity and eye movement and others show no changes or variable results [739][740][741][742][743]. These studies are mainly retrospective and small case series or reports.…”

Section: Nystagmusmentioning

confidence: 99%

BCLA CLEAR – Medical use of contact lenses

Jacobs

Carrasquillo²,

Cottrell

et al. 2021

Contact Lens and Anterior Eye

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The medical use of contact lenses is a solution for many complex ocular conditions, including high refractive error, irregular astigmatism, primary and secondary corneal ectasia, disfiguring disease, and ocular surface disease. The development of highly oxygen permeable soft and rigid materials has extended the suitability of contact lenses for such applications. There is consistent evidence that bandage soft contact lenses, particularly silicone hydrogel lenses, improve epithelial healing and reduce pain in persistent epithelial defects, after trauma or surgery, and in corneal dystrophies. Drug delivery applications of contact lens hold promise for improving topical therapy. Modern scleral lens practice has achieved great success for both visual rehabilitation and therapeutic applications, including those requiring retention of a tear reservoir or protection from an adverse environment. This report offers a practical and relevant summary of the current evidence for the medical use of contact lenses for all eye care professionals including optometrists, ophthalmologists, opticians, and orthoptists. Topics covered include indications for use in both acute and chronic conditions, lens selection, patient selection, wear and care regimens, and recommended aftercare schedules. Prevention, presentation, and management of complications of medical use are reviewed.

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Soft Contact Lenses to Optimize Vision in Adults with Idiopathic Infantile Nystagmus: A Pilot Parallel Randomized Controlled Trial

Abstract: CLs are well tolerated, with a low risk profile. Whilst our study was not powered to detect significant changes in BCVA and waveform parameters between treatment arms, we observed a trend towards an improvement in visual function at two weeks from baseline with CLs.

Cited by 14 publications

References 26 publications

Management of nystagmus in children: a review of the literature and current practice in UK specialist services

Management of nystagmus in children: a review of the literature and current practice in UK specialist services

Visual functioning in adults with Idiopathic Infantile Nystagmus Syndrome (IINS)

BCLA CLEAR – Medical use of contact lenses

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