Sol–gel methyl coating in capillary microextraction hyphenated on-line with high-performance liquid chromatography

High-temperature solvent stability of sol–gel germania triblock polymer coatings in capillary microextraction on-line coupled to high-performance liquid chromatography

“…In the past, we have used a gravity-fed sample delivery system to perform CME on sol-gel coated capillaries on-line hyphenated with HPLC [15,[17][18][19][20][21]. For these coatings, under gravity flow, extraction equilibrium was typically established after 30 to 80 min of extraction.…”

“…Sol-gel CME coatings have been effectively coupled with GC [3,[5][6][7][8][9][10], capillary electrophoresis (CE) [11,12], inductively coupled plasma mass spectrometry [13,14], and high-performance liquid chromatography (HPLC) [15][16][17][18][19][20][21]. Sol-gel coated microextraction capillaries can easily be hyphenated on-line with HPLC [15][16][17][18][19][20][21], without the need to use complex desorption devices which are required to couple fiber SPME to HPLC [22]. The majority of sol-gel coatings are silicabased.…”

An unbreakable on-line approach towards sol–gel capillary microextraction

“…This is due to the fact that the LC loop which, is usually made of stainless steel, could not be functionalized and adhesion of the coating on the inner surface of the metallic tubes are prominently physical. Malik et al were used a capillary column as a HPLC loop for coupling the sol-gel-based CME with HPLC [20][21][22][23]. Although the prepared capillary microextraction (CME) loop using the sol-gel coating resolved some issues but the extracting loop remained breakable and needed to be handled carefully.…”

Highly sensitive copper fiber-in-tube solid-phase microextraction for online selective analysis of polycyclic aromatic hydrocarbons coupled with high performance liquid chromatography

“…GC columns were early used in in-tube SPME materials since they are diverse and available for lab [11][12][13]. Then fused-silica capillary was widely applied as the tube for in-tube SPME because of the abundant active silanol groups which can be further modified to form extraction coating [14][15][16][17]. However, the extracting tube based on silica capillary is breakable and not resistant to pressure.…”