Solar and geomagnetic activity reduces pulmonary function and enhances particulate pollution effects

Anand, Kritika; Vieira, Carolina L.Z.; Garshick, Eric; Wang, Veronica; Blomberg, Annelise J.; Gold, Diane R.; Schwartz, Joel; Vokonas, Pantel; Koutrakis, Petros

doi:10.1016/j.scitotenv.2022.156434

Cited by 6 publications

(3 citation statements)

References 37 publications

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“…As CME speed parameter seems to play a critical role on the atmospheric photoionization processes and energetic particle precipitation, and on Earth's magnetic field disturbances, these factors may be linked for the observed impact on melatonin levels [23]. Intense solar activity can impact human health directly, by the modulation and disruption of the 24 h-circadian rhythm, and indirectly by inducing physicochemical properties and toxicity of atmospheric aerosols [9,12]. Solar activity continuously emits a broad-spectrum range of electromagnetic radiation that modulates changes in the solar-terrestrial environment over time scales ranging from minutes to millennia.…”

Section: Discussionmentioning

confidence: 99%

“…The disruption of 24-h circadian rhythm with concomitant reduction of melatonin synthesis and serum levels seem also to be modulated by solar and geomagnetic activity (SGA)-related visible and non-visible electromagnetic radiation [3]. This may be relevant clinically, as we have previously described reductions in pulmonary function attributable to SGA [9]. We have also observed additional adverse effects of SGA that include increases in blood pressure, atrial and ventricular arrhythmias, and increases in circulating biomarkers of systemic inflammation [10][11][12][13].…”

Section: Introductionmentioning

confidence: 97%

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Intense solar activity reduces urinary 6-sulfatoxymelatonin in patients with COPD

et al. 2023

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Background Little is known about the link between solar activity and variations in melatonin. In this study, we investigated if melatonin's major urinary metabolite, urinary 6-sulfatoxymelatonin (aMT6s), is lowest under periods of intense solar activity. Methods We investigated associations between high-energy solar particle events [Coronal Mass Ejection (CME) mass, speed and energy] on creatinine-adjusted aMT6s (aMT6sr) concentrations in 140 patients with chronic obstructive pulmonary disease (COPD) using up to four seasonal urine samples (n = 440). Mixed effect models with a random intercept for each subject were used to estimate associations, including effect modification attributable to diabetes, obesity, and reduced pulmonary function. Results Higher values of CME were associated with reduced aMT6sr concentrations, with stronger associations in patients with diabetes. An interquartile range (IQR) increase in natural log CMEspeed averaged through two days before urine collection was associated with a reduction of 9.3% aMT6sr (95%CI: − 17.1%, − 0.8%) in aMT6sr. There was a greater reduction in aMT6sr in patients with diabetes (− 24.5%; 95%CI: − 35.9%, − 11.6%). In patients without diabetes there was no meaningful association (− 2.2%; 95%CI: − 12%, 8.4%). There were similar associations with CMEenergy and CMEmass. There was no effect modification attributable to reduced pulmonary function or obesity. Conclusions This is the first study in patients with COPD to demonstrate strong detrimental impact of high-energy solar particle events on aMT6sr, with greater associations in patients with diabetes. Since melatonin is an anti-oxidant, it is possible that adverse effects of intense solar activity may be attributable to a reduction in circulating melatonin and that patients with both COPD and diabetes may be more susceptible.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

Intense solar activity reduces urinary 6-sulfatoxymelatonin in patients with COPD

et al. 2023

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“…The first one focused on air pollution and heart health of patients with cardiovascular disease, using case-crossover analysis on circulatory and respiratory hospital admissions, across the different regions in the U.S.A. (Vieira et al, 2022). The other focused on pulmonary function due to exposure to pollutants related to solar and geomagnetic activity (Anand et al, 2022).…”

Section: Day 3: Atmospheric Pollution and Healthmentioning

confidence: 99%

Insights from the first Brazilian Symposium on Human Biometeorology

Krüger,

Gomes,

Lucio

et al. 2023

Rev. Bras. Ciênc. Ambient.

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A current systematic literature review has stated several deficiencies and knowledge gaps in biometeorology research conducted in Brazil. This finding encouraged a group of local professionals in the field to foster research initiatives in topics and regions yet unexplored in the country. Motivated by that, the group organized the first Brazilian Symposium on Human Biometeorology between July 4 and 8, 2022, in Natal (RN), northeastern Brazil. This paper aims to summarize the main studies presented at the symposium and highlight a few ideas that could be pursued next in human biometeorology in future research initiatives.

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Global warming and implications for epithelial barrier disruption and respiratory and dermatologic allergic diseases

Çelebi Sözener,

Treffeisen,

Özdel Öztürk

et al. 2023

Journal of Allergy and Clinical Immunology

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Solar and geomagnetic activity reduces pulmonary function and enhances particulate pollution effects

Cited by 6 publications

References 37 publications

Intense solar activity reduces urinary 6-sulfatoxymelatonin in patients with COPD

Intense solar activity reduces urinary 6-sulfatoxymelatonin in patients with COPD

Insights from the first Brazilian Symposium on Human Biometeorology

Global warming and implications for epithelial barrier disruption and respiratory and dermatologic allergic diseases

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