Solid and cystic papillary neoplasm of pancreas: A clinic-pathological and immunohistochemical study: A tertiary care center experience

Patnayak, Rashmi; Jena, Amitabh; Parthasarathy, Sriram; Vijaylaxmi, Bodagala; Lakshmi, AY; Rukmangadha, Nandyala; Chowhan, Amit Kumar; Phaneendra, Bobbidi Venkata; Reddy, Munish

doi:10.4103/2278-330x.114141

Cited by 10 publications

(9 citation statements)

References 13 publications

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“…After surgical resection, about 95% of the patients were free of disease 1 , 15 , 19 , 21 . Only one patient had recurrence in the late postoperative follow-up, 17 months after enucleation of a pancreatic neck lesion.…”

Section: Discussionmentioning

confidence: 99%

“…The malignant potential is low and its pathogenesis is uncertain, what still motivates discussions. Corresponds to 0.17 to 3% of all malignant pancreatic cancers and affects mainly young women between the third and fourth decades of life 6 , 19 , 20 . The treatment is surgical resection and is associated with good results, favorable prognosis and the operative mortality is estimated at 2% 16 .…”

Section: Introductionmentioning

confidence: 99%

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Solid Pseudopapillary Neoplasm of the Pancreas

Carlotto

Torrez

Gonzalez

et al. 2016

ABCD, arq. bras. cir. dig.

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Background: The solid pseudopapillary neoplasm is a rare tumor of the pancreas. However, it´s etiology still maintain discussions. Aim: To analyze it´s clinical data, diagnosis and treatment. Methods: A retrospective study of medical records of all patients treated from January 1997 until July 2015. Results: Were identified 17 cases. Most patients were women (94.11%) and the average age was 32.88 years. The main complaint was abdominal mass (47.05%). The most frequent location was in the body/tail of the pancreas (72.22%) and the most frequently performed surgery was distal pancreatectomy with splenectomy (64.70%). No patient had metastases at diagnosis. Conservative surgery for pancreatic parenchyma was performed in only three cases. The rate of complications in the postoperative period was 35.29% and the main complication was pancreatic fistula (29.41%). No patient underwent adjuvant treatment. Conclusions: The treatment is surgical and the most common clinical presentation is abdominal mass. Distal pancreatectomy with splenectomy was the most frequently performed surgery for its treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Solid Pseudopapillary Neoplasm of the Pancreas

Carlotto

Torrez

Gonzalez

et al. 2016

ABCD, arq. bras. cir. dig.

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“…Numerous immunohistochemical markers were tested in SPNP. The most frequently found were: α1-antitrypsin, vimentin, α1-antichymotrypsin, neuron specific enolase (NSE), CD56 (NCAM), CD10 and PR (15,26,30,39,40). In addition to PR, the most frequent immunohistochemical markers in our series were CD10, CD 56 (NCAM), vimentin, synaptophysin and alpha-1-antitrypsin.…”

Section: Discussion Discussionmentioning

confidence: 56%

Solid Pseudopapillary Neoplasm of the Pancreas: Experience of a Tertiary Hospital

Bouca-Machado¹,

Melo²,

Lopes³

et al. 2020

SGO

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Background: Solid pseudopapillary neoplasm of pancreas is a rare tumor, predominantly affecting young women, usually with a favorable prognosis. Methods: We present a retrospective observational case-series study of eight patients diagnosed and treated in a dedicated hepatobiliary and pancreatic unit, describing the clinicopathological and immunohistochemical features. Results: seven patients were female, with a mean age of 31 years; the most frequently performed procedure was distal pancreatectomy in six cases. The lesions were well defined, with solid or mixed aspects, with 57,6 mm average size. Average follow-up is 88 months without disease recurrence or mortality records during that period. Conclusion: Given the rarity of these neoplasms, its orientation should be made only in referral centers, with multidisciplinary teams committed to pancreatic pathology.

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“…Após a ressecção cirúrgica completa, cerca de 95% dos pacientes apresentam sobrevida livre da doença após cinco anos. As recidivas tumorais são associadas principalmente a ressecções cirúrgicas com margens cirúrgicas positivas e usualmente são diagnosticadas por evidências de metástases hepáticas ou por recidiva no próprio parênquima pancreático 11 .…”

Section: Discussionunclassified

Neoplasia Pseudopapilífera Sólida de Pâncreas (Tumor de Frantz): Relato de Caso

Monção

Dias

Alcântara

et al. 2020

Rev. Bras. Cancerol.

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Introdução: A neoplasia pseudopapilífera sólida de pâncreas (tumor de Frantz) é muito rara e representa menos de 1% de todos os tumores pancreáticos. Relato do caso: Paciente do sexo feminino, 48 anos, internada para investigação de massa intra-abdominal de etiologia a esclarecer. Foi submetida a tratamento cirúrgico com sucesso na ressecção tumoral e não apresentou complicações no pós-operatório. Os pacientes usualmente tornam-se sintomáticos somente após longos períodos de evolução, quando então apresentam desconforto ou dor abdominal, ou a palpação de massas abdominais no exame físico. Para o diagnóstico, são necessários exames de imagem como ultrassonografia e tomografia computadorizada, que geralmente evidenciam volumosas massas heterogêneas intra-abdominais. É necessária a confirmação com estudo anatomopatológico e comumente estas possuem características histológicas compatíveis com tumores de baixo grau de malignidade. A ressecção cirúrgica é o tratamento recomendado e mesmo os tumores de grandes dimensões possuem chances de curas consideráveis, se for possível obter margens cirúrgicas livres. Sabe-se que a ressecção tumoral completa é associada a longos períodos de sobrevida. Conclusão: A neoplasia pseudopapilífera sólida de pâncreas (tumor de Frantz), apesar de rara, deve ser considerada no diagnóstico diferencial de tumores de pâncreas, já que o tratamento cirúrgico apresenta boas chances de cura mesmo em tumores de grandes dimensões.

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Solid and cystic papillary neoplasm of pancreas: A clinic-pathological and immunohistochemical study: A tertiary care center experience

Cited by 10 publications

References 13 publications

Solid Pseudopapillary Neoplasm of the Pancreas

Solid Pseudopapillary Neoplasm of the Pancreas

Solid Pseudopapillary Neoplasm of the Pancreas: Experience of a Tertiary Hospital

Neoplasia Pseudopapilífera Sólida de Pâncreas (Tumor de Frantz): Relato de Caso

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