Solid-pseudopapilläre Tumoren des Pankreas

Siech, M.; Merkle, Elmar M.; Mattfeldt, Torsten; Widmaier, U.; Brambs, Hans‐Jürgen; Beger, Hans G.

doi:10.1007/pl00002511

Cited by 12 publications

(19 citation statements)

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“…8 Generally speaking, there is no specific clinical syndrome for SPN of the pancreas, and the disease tends to be misdiagnosed, especially in male patients. In our study, the male patient received a misdiagnosis of chromaffin-cell tumour.…”

Section: Recherchementioning

confidence: 99%

Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases

Guo

Zhou²,

Chen³

et al. 2011

Can J Surg

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RESEARCH • RECHERCHEDiagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases Background: Our aim was to summarize our experience with the diagnosis and surgical treatment of solid pseudopapillary neoplasm (SPN) of the pancreas to provide a reference for the management of this rare condition. Methods:We collected and analyzed retrospective data on the clinical presentation, laboratory investigations, radiologic imaging, pathology and operative details of pa tients with SPN of the pancreas diagnosed between February 2001 and December 2009. Results:In all, 23 of 24 patients were women, and the mean age of all patients was 31 years. The most common clinical presentation was vague abdominal pain. Abdominal imaging showed solid or solid cystic masses in the pancreas, mostly in the tail or head of the gland. All patients were treated surgically. There were no postoperative deaths. After follow-up ranging from 4 to 109 months (median 68 mo), 20 of 22 patients who underwent curative resection were alive with no evidence of disease recurrence. Of the 2 patients with R1 resections, 1 died 42 months after surgery, whereas the other underwent a second operation and was alive after 36 months' follow-up. Conclusion:Solid pseudopapillary neoplasm of the pancreas is a relatively indolent tumour. The initial diagnosis of SPN of the pancreas is suggested by radiologic imaging findings but should be considered in the context of clinical and histopathologic characteristics. We advocate for complete surgical resection once SPN is diagnosed.Contexte : Nous voulions résumer notre expérience du diagnostic et du traitement chirurgical du néoplasme pseudo-papillaire solide (NPS) du pancréas afin d'établir un point de référence pour la prise en charge de ce problème rare.

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Section: Recherchementioning

confidence: 99%

Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases

Guo

Zhou²,

Chen³

et al. 2011

Can J Surg

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“…Capsular invasions have been described [3] and typically the preserved tumor tissue is found in the periphery, as shown here. Furthermore, tumors may infiltrate into both the sane pancreatic parenchyma and peripancreatic adipose tissue [19] . Therefore, resection according to oncological criteria should be preferred over "radical enucleation" [11] and/or local excision [20] .…”

Section: Discussion Discussion Discussion Discussion Discussionmentioning

confidence: 99%

“…Another hypothesis is that this tumor arises from pluripotent embryonic cells of the pancreas [12,14,15] or from ridges/ovarian anlage related cells, which were attached to the pancreatic tissue during early embryogenesis [16,17] . Solid-pseudopapillary tumor of the pancreas has a tendency to predominantly affect young women aged between 25 and 35 years [4,8,14,[18][19][20][21][22] . Age is reported to range from 8 [15] to 70 years [3] .…”

Section: Introduction Introduction Introduction Introduction Introducmentioning

confidence: 99%

Solid-pseudopapillary tumor of the pancreatic tail

Eder

Schulz²,

Röcken³

et al. 2005

WJG

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Abstract Abstract AbstractWe report a case of the rare solid-pseudopapillary tumor of the pancreas. In contrast to other pancreatic tumors, the solid-pseudopapillary tumor has a favorable prognosis. The 60-year-old female patient we report on here was treated by left pancreatic resection combined with splenectomy for a non-metastasizing tumor of the pancreas. A solid-pseudopapillary tumor was found on histology. The patient had no signs of metastases at present. Since a microscopically invasive tumor growth is assumed, oncologically curative resection should be preferred vs the less radical enucleation. The rare solid-pseudopapillary tumor of the pancreas has a good prognosis after successful oncological resection.

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“…It has so far been reported mainly in adults and more often in women [1][2][3][4][5][6]10]. Only a few affected children have been reported, so our experience with such a child is of interest [8].…”

mentioning

confidence: 86%

“…Pseudopapillary tumor of the pancreas is a very rare, benign pancreatic tumor, and surgical resection of the tumor is regarded as curative treatment [1][2][3][4][5][6][7][8][9][10]. It has so far been reported mainly in adults and more often in women [1][2][3][4][5][6]10].…”

mentioning

confidence: 99%