Solid pseudopapillary tumor of the pancreas: A case series of 9 patients

Abstract

While some new light has been shed on the clinicopathological features of solid pseudopapillary tumor concerning its etiology, origin and treatment methods, there is much to be understood. Further studies focusing on genetics, pathogenesis and prognosis are needed for a better understanding of this entity.

Extremely rare presentation of Frantz’s tumour: synchronous localisation in the pancreatic head and tail

“…However, Frantz first described it in 1959, and he proposed that four cases with non-functional island cell tumours were actually a new entity called 'papillary pancreas tumour'. 4,6 In general, solid pseudopapillary tumour occurs predominantly in young women and is rare in men. 6,7 Tien et al 8 reported no significant differences in patient age, size, neoplasm location or malignancy rate between the genders in solid pseudopapillary tumour.…”

“…4,6 In general, solid pseudopapillary tumour occurs predominantly in young women and is rare in men. 6,7 Tien et al 8 reported no significant differences in patient age, size, neoplasm location or malignancy rate between the genders in solid pseudopapillary tumour. By contrast, Machado et al 9 reported that cases of solid pseudopapillary tumour in men are more aggressive and that the patients are older.…”

“…Solid pseudopapillary tumours account for 1-2% of exocrine pancreas neoplasms and for 1% of all pancreas tumours and 3% of all cystic pancreas neoplasms. [4][5][6][7] There are about 800 cases reported in the English literature, and 553 cases were reported in Chinese literature studies. 2,4,6 The increasing frequency of solid pseudopapillary tumours in the last 10 years has caught much attention.…”

“…[4][5][6][7] There are about 800 cases reported in the English literature, and 553 cases were reported in Chinese literature studies. 2,4,6 The increasing frequency of solid pseudopapillary tumours in the last 10 years has caught much attention. As patients present with no specific symptoms, including abdominal pain or discomfort, poor appetite and nausea, which are related to tumour compression on adjacent organs, tumours are usually identified incidentally on routine radiological examination as ultrasound or CT. Consequently, the tumours reach large proportions at the time of identification.…”

Tumor Location Correlates with Clinicopathological Features and Prognosis of the Solid Pseudopapillary Neoplasm

“…Patients' prognosis was excellent, with a 97.1% 5-year DSS rate and a 95.7% 5-year OS rate in SEER cohort. These data basically consisted of the information reported in the former literature [ 11 , 17 ]. In comparison to tumors located in other sites, patients in the HOP group were younger than those in the OOP group.…”