Solid state characterization of mometasone furoate anhydrous and monohydrate forms

Formulation of a novel fixed dose combination of salmeterol xinafoate and mometasone furoate for inhaled drug delivery

“…The results shown in Fig. 1-1 exhibited the melting endotherms of micronized single component, which were in line with the literature [41,42]. The exothermic thermal degradation peak of MF was seen at 240°C.…”

Physical Characterization of TRK-720 Hydrate, the Very Late Antigen-4 (VLA-4) Inhibitor, as a Solid Form for Inhalation: Preparation of the Hydrate by Solvent Exchange among Its Solvates and Mechanistical Considerations

“…Quite a few studies on the behavior of solvent molecules, for example, dehydration,7–12 desolvation,13 and solvent exchange,14–18 through solvent channels have been reported. One example of solvent exchange through a channel identified by an X‐ray structural analysis involves roxithromycin,17 which can exchange acetonitrile with water at room temperature and 100%RH.…”

Polymorphism and Solvatomorphism 2005

“…The anhydrate and monohydrate phases of mometasone furoate were found to exhibit distinctly different modes of crystal packing even though the constituent molecules exhibited similar conformations 116. The anhydrate was found to crystallize in the orthorhombic P 2 1 2 1 2 1 space group, with the mometasone furoate molecules being packed tightly in the form of interlocked molecules.…”