Solid-state synthesis of Ag-doped PANI nanocomposites for their end-use as an electrochemical sensor for hydrogen peroxide and dopamine

Paulraj, P.; Umar, Ahmad; Rajendran, Kalimuthu; Manikandan, A.; Kumar, Rajesh; Manikandan, E.; Pandian, K.; Mahnashi, Mater H.; Alsaiari, Mabkhoot; Ibrahim, Ahmed A.; Bouropoulos, Nikolaos

doi:10.1016/j.electacta.2020.137158

Cited by 59 publications

(23 citation statements)

References 57 publications

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“…The sensor required lower positive potential (low overpotential) compared to traditional electrochemical sensors. The linear range was from 50 to 800 µM with good selectivity and real sample analysis results [183,185]. These works show the advantage of using ECBs compared to traditional methods in the detection of small biomolecules.…”

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 71%

“…The sensor was utilized for oxidizing DA and reducing H2O2. The proposed sensor showed a low LOD of 0.03 and 0.12 µM for H2O2 and DA, respectively [178,183]. However, UA is often detected with the help of uricase (UOx) enzyme [182,184].…”

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 99%

“…The low LOD of 0.066 µM and wide linear range of 50 to 700 µM shows the effectiveness of using UOx enzyme in the modification process [182,184]. In another work, an AuNP and rGO complex was utilized for the immobilization of UOx [183,185]. This biosensor was utilized for the rapid detection of UA from human serum samples.…”

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 99%

“…Unlike H 2 O 2 and glucose, there is no specific biocatalyst that is employed for the detection of DA. Paulraj and coworkers showed that polyaniline (PANI)-coated AgNP-modified electrodes can be used for simultaneously detecting DA and H 2 O 2 [178,183]. The sensor was utilized for oxidizing DA and reducing H 2 O 2 .…”

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 99%

“…Such surface immobilization of BRCs (antibody, peptide, or aptamer) for preparing immune/aptasensors depends on the functionality of the biomolecule and the type of nanostructured electrode modifiers used. Both of these need to be compatible with each other [62,155,179,183]. For example, AuNPs allow thiol-functionalized antibody/aptamers to be anchored over the electrode surface via activation of the thiol group (SH)-Au bond, which is one of the fundamental pathways followed in most electrochemical bioaffinity sensor preparations [97,152].…”

Section: Mnps In Cancer Biomarker Detectionmentioning

confidence: 99%

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Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

et al. 2020

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With the rise in public health awareness, research on point-of-care testing (POCT) has significantly advanced. Electrochemical biosensors (ECBs) are one of the most promising candidates for the future of POCT due to their quick and accurate response, ease of operation, and cost effectiveness. This review focuses on the use of metal nanoparticles (MNPs) for fabricating ECBs that has a potential to be used for POCT. The field has expanded remarkably from its initial enzymatic and immunosensor-based setups. This review provides a concise categorization of the ECBs to allow for a better understanding of the development process. The influence of structural aspects of MNPs in biocompatibility and effective sensor design has been explored. The advances in MNP-based ECBs for the detection of some of the most prominent cancer biomarkers (carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), Herceptin-2 (HER2), etc.) and small biomolecules (glucose, dopamine, hydrogen peroxide, etc.) have been discussed in detail. Additionally, the novel coronavirus (2019-nCoV) ECBs have been briefly discussed. Beyond that, the limitations and challenges that ECBs face in clinical applications are examined and possible pathways for overcoming these limitations are discussed.

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Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 71%

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 99%

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 99%

Section: Mnps In Small Biomolecule Sensingmentioning

confidence: 99%

Section: Mnps In Cancer Biomarker Detectionmentioning

confidence: 99%

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Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

et al. 2020

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Hybrid Materials Based on Conducting Polymers for Nitrite Sensing: A Mini Review

Salhi¹,

Ez-zine²,

Rhazi³

2021

Electroanalysis

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Well‐known as a hazardous compound, nitrite constitute a real threat to the public health. So, there is a pressing need to detect and quantify them in different matrix. Even though conventional analytical methods can be used to address this issue, electrochemistry allows a fast, sensitive, and efficient analysis. Conducting polymers continue to raise great interest among scientific communities due to their properties. Moreover, their combination with carbon nanomaterials, or metallic nanoparticles improves their properties, and provides great results. In this paper, we will focus on some revealing works devoted to the electrochemical detection of nitrite using this kind of materials.

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Electroconductive Green Metal‐polyaniline Nanocomposites: Synthesis and Application in Sensors

Kyomihumbo

Feleni

2022

Electroanalysis

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Polyaniline (PANI) is one of the most extensively used conducting polymer due to its fascinating properties including conducting, thermal, optical, magnetic and electrochemical properties, simple synthesis procedure and low cost of monomer. It has attracted major attention in a variety of applications including electrochemical sensors, catalysts, supercapacitors and biosensors. However, its limitations such as insolubility in common solvents, low process‐ability and poor mechanical properties have led to the development of new approaches to improve it properties. Metal nanoparticles (MNPs) such as silver, gold, copper and palladium have been combined with PANI to improve on its properties which has led to a new class of materials known as metal/PANI nanocomposites. These hybrid nanocomposites incorporate advantages of both MNPs and polymers which effectively improves the properties of the individual materials. Various synthesis techniques including in situ polymerization, ɤ‐radiolysis, electrodeposition, complexation, vacuum deposition and interfacial polymerization have been used in the formation of metal/PANI nanocomposites. These nanocomposites have been used in various sensor and biosensor applications due to their excellent conductivity, ease of synthesis, excellent redox potentials, chemical and thermal stability. This review highlights the various metal/PANI nanocomposites, their various synthesis techniques and their application in sensors and biosensors. The importance of these nanocomposites in sensing and signaling various toxic heavy metals such as mercury, lead and silver and toxic gases such as hydrogen sulphide, ammonia and chloroform has been discussed. In addition the review covers the applications of metal/PANI nanocomposites in biosensor systems for the detection of glucose, DNA, protein, cholesterol, drugs and hydrogen peroxide.

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Solid-state synthesis of Ag-doped PANI nanocomposites for their end-use as an electrochemical sensor for hydrogen peroxide and dopamine

Cited by 59 publications

References 57 publications

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

Hybrid Materials Based on Conducting Polymers for Nitrite Sensing: A Mini Review

Electroconductive Green Metal‐polyaniline Nanocomposites: Synthesis and Application in Sensors

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