Solitary Idiopathic Choroiditis

Monteiro, Sérgio; Andrews, Richard M.; Sagoo, Mandeep S.

doi:10.1159/000357470

Cited by 9 publications

(3 citation statements)

References 17 publications

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“…This is in contrast to the cohort of 60 cases reported by Shields et al [2], in which most patients presented with symptoms, with about onethird of all lesions showing signs of inflammation. Notably, gamma-interferon testing was not available at the time of publication of this series [8]. As none of our cases showed any evidence of ocular inflammation, we can only surmise that the lesions in this series must have a different pathology.…”

Section: Discussionmentioning

confidence: 73%

A Case Series of “Solitary Idiopathic Choroiditis” and Proposal of a Nomenclature Change to “Idiopathic Scleroma”

et al. 2020

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Objective: To define the characteristics of solitary idiopathic choroiditis (SIC) in a consecutive series of patients and propose a nomenclature change to idiopathic scleroma. Materials and Methods: Electronic patient records were retrospectively interrogated to identify all patients diagnosed with SIC between 2002 and 2019 in a tertiary referral ophthalmic hospital in the United Kingdom. Results: Thirty-four eyes of 34 patients were found to have SIC. The mean age at diagnosis was 48 years (range 24–78) and 23 patients (68%) were female. All lesions were located posterior to the equator, most frequently in the inferotemporal quadrant (13 eyes, 38%). The lesions had a mean largest basal diameter of 1.2 ± 0.4 disc diameters (range 0.5–2) and their distance to the optic disc had a mean of 1.2 ± 0.9 disc diameters (range 0–3.3). All lesions were intrascleral on enhanced depth imaging optical coherence tomography, demonstrating a hypo-reflective zone within the sclera, with an underlying hyper-reflective zone in some cases. No lesion enlarged or developed features consistent with active inflammation after a median follow-up time of 0.9 years (range 0–16.8). Discussion/Conclusion: Optical coherence tomography shows SIC to be an intrascleral lesion. Furthermore, we found no evidence of any inflammatory component. A nomenclature change to idiopathic scleroma is appropriate to prevent unnecessary investigation.

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Section: Discussionmentioning

confidence: 73%

A Case Series of “Solitary Idiopathic Choroiditis” and Proposal of a Nomenclature Change to “Idiopathic Scleroma”

et al. 2020

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“…In the report by Kohne et al., they described a patient whose lesion mildly improved with no intervention six months later, but the lesion was likely inactive at presentation due to lack of surrounding fluid and distinct margins seen in the later phases of FA, features of activity [5]. Other case reports of FSN in the literature do not follow the patients longitudinally or present patients who have already received treatment making any extrapolation of natural history of the lesions impossible [6][7][8]. Understanding the evolution of active lesions can provide prognostic value and contribute to the recommendations of future treatment guidelines of FSN as we hope this case report does; however, as with any case report, this represents only a single case and broad generalizations cannot be drawn.…”

Section: Discussionmentioning

confidence: 99%

The evolution of an active solitary idiopathic choroiditis (focal scleral nodule): a case report of the natural course and a review of the literature

2021

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Background To describe the clinical course of an active solitary idiopathic choroiditis (focal scleral nodule) that nearly resolved over six weeks without intervention. Case presentation An 18-year-old man presented to the emergency department with headaches and new onset central scotoma in the right eye. Visual acuity was 20/20 in both eyes. Fundus examination revealed an amelanotic choroidal lesion with associated shallow subretinal fluid. It measured 6.1 × 6.3 × 1.4mm on A- and B-scan. Evaluation for systemic inflammatory and infectious diseases was negative. A week later, the lesion remained stable, and a month later, there was improvement of the lesion with a decrease in size on OCT and exam and resolution of the subretinal fluid suggesting that the lesion had become inactive. Conclusions Solitary idiopathic choroiditis (Focal scleral nodule) is a rare condition characterized by inflammatory granulomatous reaction. This case report sheds light on the unknown natural course of a solitary idiopathic choroiditis (focal scleral nodule).

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“…Literatürde "soliter idiyopatik koroidit" terimi de bu spektrumdaki lezyonları tarif etmek için kullanılmaktadır. [1][2][3] İdiyopatik koroidal granulom tanısı bir dışlama tanısıdır. Kroidal granuloma neden olan sarkoidoz, tüberküloz, sfiliz, kedi tırmığı hastalığı, toksokara, histoplazmozis, toksoplazma ve posterior nodüler sklerit gibi nedenler dışlandıktan sonra idiyopatik koroidal granulom tanısı düşünülmelidir.…”

Section: Idiyopatik Koroidal Granülomunclassified

Pediatric Mass Lesions of the Fundus

2023

Güncel Retina (Current Retina)

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In this review, clinical findings, diagnosis, and treatments of pediatric mass lesions of the fundus were summarized which are seen less often. Idiopathic choroidal granuloma, medulloepithelioma, juvenile xanthogranuloma, fibrous histiocytoma, intraocular teratoma, and ophthalmic findings of Klippel–Trenaunay–Weber syndrome were summarized. These lesions should be kept in the mind for differential diagnosis during ocular oncology practice.

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Solitary Idiopathic Choroiditis

Cited by 9 publications

References 17 publications

A Case Series of “Solitary Idiopathic Choroiditis” and Proposal of a Nomenclature Change to “Idiopathic Scleroma”

A Case Series of “Solitary Idiopathic Choroiditis” and Proposal of a Nomenclature Change to “Idiopathic Scleroma”

The evolution of an active solitary idiopathic choroiditis (focal scleral nodule): a case report of the natural course and a review of the literature

Pediatric Mass Lesions of the Fundus

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