Solubilities of dialkylhydrogen phosphonates in supercritical carbon dioxide and their correlation using semi-empirical equations

Deepitha, J.; Pitchaiah, K.C.; Rao, C. V. S. Brahmmananda; Madras, Giridhar; Sivaraman, N.

doi:10.1080/01496395.2018.1538244

Cited by 23 publications

(10 citation statements)

References 44 publications

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“…Among various models considered in this work, we examined the goodness of the model through Akaike’s information criterion (AIC). Mathematically, AIC could be expressed as − In eq , σ 2 , Q , and N are SSE/ N and constants in the individual model and number of observations, respectively.…”

Section: Resultsmentioning

confidence: 99%

Solubility of Amlodipine Besylate (Calcium Channel Blocker Drug) in Supercritical Carbon Dioxide: Measurement and Correlations

Sodeifian¹,

Garlapati

Razmimanesh³

et al. 2021

J. Chem. Eng. Data

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Section: Resultsmentioning

confidence: 99%

Solubility of Amlodipine Besylate (Calcium Channel Blocker Drug) in Supercritical Carbon Dioxide: Measurement and Correlations

Sodeifian¹,

Garlapati

Razmimanesh³

et al. 2021

J. Chem. Eng. Data

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“…The models used in correlation exercise are having varying number of parameters and the best model is obtained with the help of Akaike's information criterion (AIC) [55][56][57][58][59] . The data used in this exercise is small (N<40), hence corrected AIC (AICc) is used for the identifying the best model.…”

Section: Resultsmentioning

confidence: 99%

Measurement and Modeling of Clemastine Fumarate (Antihistamine Drug) Solubility in Supercritical Carbon Dioxide

Sodeifian

Garlapati²,

Razmimanesh

et al. 2021

Preprint

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The solubilities of clemastine fumarate in supercritical carbon dioxide) ScCO2( were measured for the first time at temperature (308 to 338 K) and pressure (12 to 27 MPa). The measured solubilities were reported in terms of mole faction and it is ranged from 1.61 ×10− 6 to 9.41×10− 6. Various models were used to correlate the data. The efficacy of the models was quantified with corrected Akaike’s information criterion (AICc). A new cluster salvation model was derived to correlate the solubility data. The new model was able to correlate the data and deviation was 10.3% in terms of average absolute relative deviation (AARD). Furthermore, the measured solubilities were also correlated with existing K.-W. Chen et al., cluster salvation model, equation of state (EoS) model and few density models. Among density models, Tippana and Garlapati model was observed to be the best model and corresponding AARD% was 7.57 (corresponding AICc is -678.88). The Peng-Robinson equation of state as temperature independent was able to correlate the data and deviation was 8.25% in terms of AARD% (corresponding AICc is -674.88). Moreover, thermodynamic enthalpies of clemastine fumarate were estimated.

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“…The experimental procedure adopted for the determination of solubility of PPA in SCCO 2 medium was explained in detail elsewhere. 43,44 2.2.1.1. Solubility of PPA in Neat SCCO 2 Medium.…”

Section: Methodsmentioning

confidence: 99%

“…The apparatus consists of a carbon dioxide cylinder, carbon dioxide pump, methanol pump, high-pressure equilibrium cells (10 mL capacity), thermostat, automatic back-pressure regulator (BPR), and a collection unit. The experimental procedure adopted for the determination of solubility of PPA in SCCO 2 medium was explained in detail elsewhere. , …”

Section: Methodsmentioning

confidence: 99%

“…The accurate determination of the solubility of PPA in SCCO 2 depends on the saturation of PPA in CO 2 phase. Flow rates of CO 2 were optimized in our earlier studies to achieve the saturation solubility. ,, In the present study, all solubility measurements were carried with 0.1–0.2 mL/min (CO 2 flow rate) to ensure the saturation of SCCO 2 with PPA. Based on the solute collected for an appropriate time period (after saturation solubility is achieved), amounts of CO 2 and methanol passed, and the solubilities are calculated.…”

Section: Methodsmentioning

confidence: 99%

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Solubility of Phenylphosphinic Acid in Supercritical Carbon Dioxide and the Influence of Methanol on the Solubility Behavior

2019

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The solubility of phenylphosphinic acid (PPA) was measured for the first time in supercritical carbon dioxide (SCCO2) at 313, 323, and 333 K with pressure ranging from 10–20 MPa using a dynamic flow technique. The solubility of PPA in neat SCCO2 ranged from 0.1 × 10–5 to 18 × 10–5 mol/mol. The influence of cosolvent, methanol, on solubility behavior was studied by measuring the solubility of PPA in SCCO2 + methanol medium (1 and 4 mol % methanol) at 313 and 323 K with pressure varying from 10–20 MPa. The highest solubility of PPA in the SCCO2 + methanol mixture is 29.4 × 10–4 mol/mol at 313 K and 20 MPa with a methanol composition of 4 mol %. The solubilities in neat SCCO2 were correlated using different semiempirical equations (Mendez–Teja, Chrastil, and Bartle) with an average deviation of <10%. The solubility in the presence of methanol was correlated with four semiempirical/empirical models (modified Chrastil, modified Mendez–Teja, Garlapati model, and Jouyban equation); among these models, Jouyban model resulted in better correlation with an average deviation of 5%.

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Solubilities of dialkylhydrogen phosphonates in supercritical carbon dioxide and their correlation using semi-empirical equations

Cited by 23 publications

References 44 publications

Solubility of Amlodipine Besylate (Calcium Channel Blocker Drug) in Supercritical Carbon Dioxide: Measurement and Correlations

Solubility of Amlodipine Besylate (Calcium Channel Blocker Drug) in Supercritical Carbon Dioxide: Measurement and Correlations

Measurement and Modeling of Clemastine Fumarate (Antihistamine Drug) Solubility in Supercritical Carbon Dioxide

Solubility of Phenylphosphinic Acid in Supercritical Carbon Dioxide and the Influence of Methanol on the Solubility Behavior

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