Solution structure and behaviour of Δ-cis-α-[Ru(R,R-picchxnMe2)(phi)]2+ by NMR spectroscopy and molecular modellingElectronic supplementary information (ESI) available: NMR spectra and selected NMR data. See http://www.rsc.org/suppdata/dt/b2/b208846k/

A spectroscopic investigation of the self-association and DNA binding properties of a series of ternary ruthenium(II) complexes

“…The metal ion provides a substitutionally inert octahedral geometry and the bidentate serves as the intercalating chromophore [27]. We have shown using 1 H NMR spectroscopy that some complexes of the general form [Ru(N 4 -tetradentate)(N 2 -bidentate)] 2+ self-associate in aqueous solution in a manner consistent with the intermolecular p-stacking of the bidentate ligands [10,24,28]. Here, we report the synthesis, selfassociation and DNA binding properties of six Ru(II) complexes formed from combinations of the tetradentate ligands 1,6-di(2 0 -pyridyl)-2,5-dimethyl-2,5-diazahexane (PicenMe 2 ), 1,6-di(2 0 -pyridyl)-2,5-dibenzyl-2,5-diazahexane (PicenBz 2 ) and the bidentate ligands 2,2 0 -bipyridine (bipy), 1,10-phenanthroline (phen) and dipyrido[3,2-f:2 0 3 0 -h]quinoxaline (dpq) (structures in Fig.…”

“…The dimer association constant values indicate a clear tendency for these compounds to form heterochiral dimers [5]. The self-association of D-cis-a-[Ru(R,R-picchxnMe 2 )(phi)] 2+ (where picchxnMe 2 is equivalent to picenMe 2 , except that the ethane bridge is replaced with a cyclohexane unit and phi is 9,10-phenanthrenequinonediimine 9) was studied from aqueous solutions [28]. The results of these studies indicated that at 25 mM this complex formed aggregates for which the average molecular weight was three times that of the monomer.…”

Oligopyridine–ruthenium(ii)–amino acid conjugates: synthesis, characterization, DNA binding properties and interactions with the oligonucleotide duplex d(5′-CGCGCG-3′)2

“…63 On the other hand, molecules that bind in the DNA grooves interact with the ends of the bases causing upfield shifts smaller than 0.2 ppm to the molecule proton resonances. 64 From Fig. 8 and 9 it is observed that the proton signals of the ancillary bpy ligands in the cases of D-diastereomers show higher upfield shifts than those of the corresponding K-diastereomers.…”

Minimising sample volume and run times for circular dichroism spectroscopy

“…Materials D-Cis-a-[Ru(R,R-picchxnMe 2 )phdi]Cl 2 , where picchxnMe 2 ¼ N,N 0 -dimethyl-N,N 0 -di(2-picolyl)-1,2-diaminocyclohexane and phdi ¼ 9,10-phenanthrenediimine 4,5 was kindly provided by Peter Karuso. Solutions were made up to a concentration that kept the high-tension voltage on the Jasco J-1500 below 600 V as This journal is © The Royal Society of Chemistry 2022…”