2021
DOI: 10.1101/2021.03.25.436920
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Somatic junctions connect microglia and developing neurons

Abstract: Microglia are the resident immune cells of the brain with multiple homeostatic and regulatory roles. Emerging evidence also highlights the fundamental transformative role of microglia in brain development. While tightly controlled, bi-directional communication between microglia and neuronal progenitors or immature neurons has been postulated, the main sites of interaction and the underlying mechanisms remain elusive. By using correlated light and electron microscopy together with super-resolution imaging, here… Show more

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