Some Acenaphthene Compounds

Abstract

A new geometric isomer of 1,2-dichloroacenaphthene has been isolated among the reaction products of acenaphthylene and hypochlorous acid. Some new derivatives of acenaphthenone and acenaphthenol are reported.

Conversions of .alpha.-methyl to .alpha.-methylene-.gamma.-lactones. Synthesis of two allergenic sesquiterpene lactones. (-)-Frullanolide and (+)-arbusculine B

“…However, the hydroxy salt 12, obtained by treatment of 11 with KOH in 95% EtOH, was much less prone to hydrogenolysis. 29 The salt 12 was stirred with W-2 Raney nickel (10 ml/g of 11) in 95% EtOH (or MeOH) containing KOH at -25°and the mixture was then acidified and chromatographed to give 110(H), 11,12-dihydrofrullanolide (13)30 in better than 40% overall yield. A second nonacidic product, tentatively identified as lactone 14, was formed in about 10% yield.…”