Some histopathological effects of Aroclor 1254 on the liver and gonads of rainbow trout, Salmo gairdneri and carp, Cyprinus carpio

Abstract

Sexually mature and 9 rainbow trout (Salmo gairdneri Richardson) and carp (Cyprinus carpio L.) were injected intraperitoneally with Aroclor 1254 (25 mg kg-' body weight in 1 ml of arachis oil) once weekly for four weeks. Arachis oil was used as the control. At the end of the fourth week, samples of the liver, testis and ovary were taken from treated and control fish and examined by light and electron microscopy. The light microscope study indicated that there was general vacuolation of the hepatocytes of trout but not carp; fragmentation of the developing oocytes but no observable changes in the testis. Electron microscopy study showed that there was enlargement of the rough endoplasmic reticulum of the hepatocytes, some damage to spermatozoa and proliferation of the smooth endoplasmic reticulum of the oocytes.

Effects of Polychlorinated Biphenyls on Liver Ultrastructure, Hepatic Monooxygenases, and Reproductive Success in the Barbel

“…The cell organization observed in control barbel hepatocytes is classic and quite comparable to that observed in other fish hepatocytes (e.g., Hacking et al, 1977;Sivarajah et al, 1978;Ko¨hler, 1990). The absence of SER and Golgi apparatus has also been noted previously (Chapman, 1981) in rainbow trout.…”

Polychlorinated biphenyls, mercury, and potential endocrine disruption in fish from the Hudson River, New York, USA

“…Median concentrations of E2 in male and female carp were inversely correlated with sediment PCB residues in Woods Pond, Massachusetts (Smith et al, 2002). Antiandrogenic and PCBs, HG, and endocrine disruption in Hudson fish antiestrogenic effects were observed in carp after four weeks of intraperitoneal injections of Aroclor 1254; concentrations of estrogens and androgens in blood of female and male were significantly reduced (Sivarajah et al, 1978a); developing oocytes became fragmented and spermatozoa were damaged (Sivarajah et al, 1978b).…”

Histopathological changes in the gonads, liver, and kidney of Glossogobius giuris exposed to sub-lethal concentration of diazinon

“…At 0.032 and 0.064 ppm of diazinon, karyolysis and fragmented ovary and testis with abnormal shape and arrangement were observed which agreed with the findings of Hossain et al (2002). Sivarajah et al (1978) also reported similar type of fragmentation and karyolysis in the ovaries of Salmo gairdneri and Cyprinus carpio when exposed to the organochlorine pesticide, Aroclor. The liver of G. giuris in the control was normal without necrosis, hepatocytes and other cells were normal and systematically arranged.…”